PREQUEL
UREA ADVANCED RELIEF
UREA ADVANCED RELIEF
PREQUEL
urea-advanced-relief
Moisturize
9873693770021
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Highlights
WHAT IS IT?
Face and body moisturizing lotion with 10% urea
FEATURES
24-hour moisture, Clinically tested, Restoring formula, Reestablishes optimal hydration
BEST FOR
dry
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Who Is It For?
All Ages And GendersWhat Does It Help With?
Dry Skin Rough Skin Itchy Skin Flaky Skin Skin HydrationBudget
Affordable (under $30)How To Use
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Key Information
What PREQUEL Says
Product Description:
CLINICALLY TESTED 24 HOUR MOISTURE. A restoring face and body urea lotion that reestablishes optimal levels of hydration. Formulated with 10% pure urea, this moisturizer nourishes skin to soothe dry, rough, itchy, and flaky skin. Added shea butter, glycerin, and niacinamide smooth and tone for healthier looking skin.
About the Brand:
Ingredients Overview
Ingredients List
urea, shea-butter, glycerin, niacinamide
Key Ingredients
urea 10%, shea butter, glycerin, niacinamide
Ingredients Details
Urea
Common Name(s): Urea,nmf component keratolytic,dual humectant+exfoliant
CAS Number: N/a
DESCRIPTION
What It Does: At 2โ10%: provides deep humectancy, softens sc, and improves other active penetration. at 10โ40%: keratolytically dissolves corneocyte protein bonds for intensive exfoliation of hyperkeratotic skin (calluses, eczema plaques, psoriasis).
Why It's Used: Urea combines two otherwise separate ingredient classes (humectant and keratolytic) in one molecule, with formulator-controlled function through concentration selection โ uniquely versatile for multiple skin condition applications.
How It Works: Urea's carbonyl and amine groups form h-bonds with water (humectancy) and with corneocyte keratin (penetration). at high concentrations, urea disrupts keratin hydrogen bonds (chaotropic activity) solubilising the sc protein matrix โ concentration determines whether humectant or keratolytic effect predominates.
Typically Found In: Eczema,hyperkeratosis,callus care,moisturising
TECHNICAL DETAILS
Primary Category: Functional ingredient โ humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 2%โ40%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Urea is the most concentrated natural nmf component โ healthy sc contains 28 mg/g urea versus 2 mg/g in xerotic (dry) skin. topical urea application directly replenishes the physiological nmf deficit that drives dry skin conditions.
Last Verified: Cosing database,urea nmf dual function humectant keratolytic review
Primary Sources: 2026-03-12