
Highlights
WHAT IS IT?
Ampoule balm stick with probiotics
FEATURES
Multi-purpose balm stick, contains 77.2% Extreme Biome, formulated with 10 different probiotics, uses EXTREME FERMENT ฮฑโข Method
BEST FOR
Normal to dry skin
CHECKS
Free of parabens, phthalates
Who Is It For?
Adults (default) Both Men And WomenWhat Does It Help With?
Multiple Signs Of Aging Fine Lines Wrinkles Hydration Firmness Elasticity Radiance BrighteningBudget
Mid-rangeHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Time Revolution Says
Product Description:
Missha's best-selling ampoule comes in a multi balm stick! Time Revolution Night Repair Ampoule Balm Stick effectively cares for multiple signs of aging like fine lines and wrinkles. This nourishing serum is infused with 77.2% Extreme Biome, formulated with 10 different probiotics to help strengthen & hydrate, firm & lift, improve elasticity & radiance, and brighten & soften skin overnight. Ingredients are fermented with Missha's EXTREME FERMENT ฮฑโข Method, a unique three-step fermentation method that stably delivers an extreme boost of active ingredients to the skin.
About the Brand:
Ingredients Overview
Ingredients List
HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, POLYGLYCERYL-2 TRIISOSTEARATE, OCTYLDODECANOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, MACADAMIA SEED OIL POLYGLYCERYL-6 ESTERS BEHENATE, EUPHORBIA CERIFERA (CANDELILLA) WAX, MICROCRYSTALLINE WAX, BIS-DIGLYCERYL POLYACYLADIPATE-2, TOCOPHERYL ACETATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, SYNTHETIC WAX, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, RICINUS COMMUNIS (CASTOR) SEED OIL, POLYETHYLENE, VINYL DIMETHICONE/METHICONE SILSESQUIOXANE CROSSPOLYMER, BORAGO OFFICINALIS SEED OIL, TRIOCTYLDODECYL CITRATE, BISABOLOL, CITRUS AURANTIUM BERGAMIA (BERGAMOT) FRUIT OIL, SILICA, TOCOPHEROL, ECLIPTA PROSTRATA EXTRACT, PELARGONIUM GRAVEOLENS FLOWER OIL, DEHYDROACETIC ACID, HIPPOPHAE RHAMNOIDES FRUIT OIL, MELIA AZADIRACHTA LEAF EXTRACT, LAVANDULA ANGUSTIFOLIA (LAVENDER) OIL, CITRUS AURANTIUM DULCIS (ORANGE) PEEL OIL, MELIA AZADIRACHTA FLOWER EXTRACT, MORINGA OLEIFERA SEED OIL, WATER, COCCINIA INDICA FRUIT EXTRACT, SOLANUM MELONGENA (EGGPLANT) FRUIT EXTRACT, ALOE BARBADENSIS FLOWER EXTRACT, SQUALANE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, ANTHEMIS NOBILIS FLOWER OIL, SANTALUM ALBUM (SANDALWOOD) OIL, CURCUMA LONGA (TURMERIC) ROOT EXTRACT, CORALLINA OFFICINALIS EXTRACT, OCIMUM SANCTUM LEAF EXTRACT, BEESWAX, BUTYLENE GLYCOL, HYDROGENATED LECITHIN, 1,2-HEXANEDIOL, SORBITAN SESQUIOLEATE, LUPINUS ALBUS SEED EXTRACT, SUCROSE TETRASTEARATE TRIACETATE, GLYCERIN, LACTOBACILLUS FERMENT, DAUCUS CAROTA SATIVA (CARROT) ROOT EXTRACT, VACCINIUM ANGUSTIFOLIUM (BLUEBERRY) FRUIT EXTRACT, BETA VULGARIS (BEET) ROOT EXTRACT, BRASSICA OLERACEA CAPITATA (CABBAGE) LEAF EXTRACT, SORBITAN STEARATE, SORBITAN OLIVATE, PANTHENOL, SUCROSE DISTEARATE, ALCOHOL, CAPRYLYL GLYCOL, MADECASSOSIDE, METHICONE, GLYCERYL CITRATE/LACTATE/LINOLEATE/OLEATE, HYDROGENATED POLYISOBUTENE, CHOLESTEROL, ETHYLHEXYLGLYCERIN, CERAMIDE NP, ADENOSINE, BIFIDA FERMENT LYSATE, ALPINIA GALANGA EXTRACT, PENTYLENE GLYCOL, LACTOBACILLUS/PUNICA GRANATUM FRUIT FERMENT EXTRACT, LACTOBACILLUS/ACEROLA CHERRY FERMENT, LACTOBACILLUS/SOYBEAN FERMENT EXTRACT, LACTOBACILLUS FERMENT LYSATE, LACTOCOCCUS FERMENT, LACTOCOCCUS FERMENT LYSATE, LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE, BIFIDA FERMENT FILTRATE, HYDROLYZED COLLAGEN, SODIUM HYALURONATE, ORYZA SATIVA (RICE) EXTRACT, SACCHAROMYCES FERMENT, XANTHAN GUM, BACILLUS FERMENT
Key Ingredients
Extreme Biome (77.2%), 10 different probiotics
Ingredients Details
Bis-diglyceryl Polyacyladipate-2
Common Name(s): Bis-diglyceryl polyacyladipate-2,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function at recommended use concentration.
Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.
How It Works: Works through the mechanism of its molecular class โ physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Bis-diglyceryl polyacyladipate-2 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.
Last Verified: Cosing database,bis-diglyceryl polyacyladipate-2 technical literature
Primary Sources: 2026-03-12
Butyrospermum Parkii Shea Butter
Common Name(s): Butyrospermum parkii shea butter
DESCRIPTION
What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.
Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.
How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ enzymes, receptors, structural proteins, or signaling molecules โ triggering beneficial biological responses.
Typically Found In: Serums,treatments,moisturizers,specialty products
TECHNICAL DETAILS
Primary Category: Specialty actives
Secondary Functions: Skin-conditioning,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Specialty active ingredient; check individual sourcing for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1899-12-31 00:00:00 -0800
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides
Avoid Combining With: Incompatible with oxidizing agents; check ph stability
SCIENTIFIC NOTE
Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Euphorbia Cerifera Candelilla Wax
Common Name(s): Euphorbia cerifera candelilla wax
DESCRIPTION
What It Does: Provides antioxidant protection, soothing anti-inflammatory effects, and skin-conditioning benefits through plant-derived polyphenols and phytochemicals.
Why It's Used: Plant extracts concentrate bioactive phytochemicals evolved for environmental protection โ uv, microbial, and oxidative stressors โ that translate to skin benefits.
How It Works: Polyphenols (flavonoids, phenolic acids) inhibit nf-ฮบb-mediated inflammatory signaling, scavenge reactive oxygen species through electron donation, and chelate pro-oxidant metal ions to reduce oxidative skin damage.
Typically Found In: Lipsticks,balms,creams,deodorants
TECHNICAL DETAILS
Primary Category: Waxes
Secondary Functions: Emollient,film former
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1โ40%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived or synthetic wax; check source for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1899-12-31 00:00:00 -0800
Comedogenicity Rating: 1899-12-31 00:00:00 -0800
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Other waxes,emollients,pigments
Avoid Combining With: Strongly alkaline conditions
SCIENTIFIC NOTE
Plant secondary metabolites (flavonoids, terpenes, phenolic acids) are biosynthesized as defense compounds against uv, herbivores, and pathogens. their anti-inflammatory activity typically derives from competitive inhibition of cox-2 and 5-lox enzymes (ic50 1โ50 ยตm), while antioxidant activity involves single electron transfer (set) and hydrogen atom transfer (hat) mechanisms with structure-dependent rate constants.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Helianthus Annuus (sunflower) Seed Oil
Common Name(s): Helianthus annuus (sunflower) seed oil,botanical oil,phytochemical active
CAS Number: N/a
DESCRIPTION
What It Does: Provides antioxidant protection from reactive oxygen species, reduces inflammatory cytokine production in skin, and conditions skin through the plant's phytochemical complex.
Why It's Used: Natural origin narrative, traditional use heritage, and multi-functional phytochemical profile supporting concurrent skin care claims from one ingredient.
How It Works: Polyphenols, terpenoids, and alkaloids scavenge ros via hโข donation, inhibit nf-kb or cox-2 inflammatory pathways, and interact with skin surface proteins for conditioning.
Typically Found In: Botanical skin care,natural products
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Plant secondary metabolites evolved as photoprotectants and antimicrobials โ mechanisms directly applicable to cosmetic antioxidant and anti-inflammatory activity in human skin.
Last Verified: Cosing database,helianthus annuus (sunflower) seed botanical review
Primary Sources: 2026-03-12