The Ordinary Retinol 0.5% In Squalane

Nykaa E retail limited

The Ordinary Retinol 0.5% In Squalane

The Ordinary Retinol 0.5% In Squalane

Nykaa E retail limited

the-ordinary-retinol-0-5-in-squalane

Serum

10084981244197

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Compatibility Score

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Highlights

WHAT IS IT?

Retinol serum with 7 ingredients

FEATURES

Moderate strength retinol; targets signs of aging, dryness, textural irregularities, uneven skin tone; water-free; contains moisturizing squalane; improves fine and dynamic lines and skin texture; refrigerate after opening; use within three months; use sun protection

BEST FOR

all skin types

CHECKS

Does not contain other retinoids, suitable for sensitive skin with caution, no artificial preservatives

Who Is It For?

What Does It Help With?

Signs Of Aging Dryness Uneven Skin Tone Texture Irregularities Fine Lines

Budget

Mid-range ($30-$75)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Apply a few drops in the evening. Do not use with other retinoid products. Use sun protection during the day. Refrigerate after opening. Patch test prior to use is advised.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Nykaa E retail limited Says

Product Description:

A moderate-strength retinol serum that targets general signs of skin aging. Targets: Signs of aging, dryness, textural irregularities, uneven skin tone. Suited to: All skin types. Format: Anhydrous Solution. Key Ingredients: Retinol, Squalane. Retinol 0.5% in Squalane offers a water-free solution containing 0.5% retinol, an ingredient that improves the appearance of fine and dynamic lines from loss of collagen and elastin, while evening skin texture and tone. The formula is supported with squalane, a moisturizing agent that enhances surface-level hydration and helps combat dryness associated with retinol use. Note: Refrigerate after opening and use within three months. Caution: Retinoids increase skin sensitivity to UV radiation; sun protection is important. Do not use with other retinoids. Not a treatment for acne. Avoid use during pregnancy or breastfeeding.

About the Brand:

Revolutionizing skincare transparency, The Ordinary offers clinical formulations with established technologies at radical price points. Founded by Brandon Truaxe under DECIEM in 2016, this disruptive brand focuses on single-ingredient integrity and scientific communication. Experience advanced actives without marketing hype or inflated costs through straightforward formulations that democratize effective skincare.

Ingredients Overview

Ingredients List

Squalane,Caprylic/Capric-Triglyceride,Simmondsia-Chinensis-(Jojoba)-Seed-Oil,Retinol,Solanum-Lycopersicum-(Tomato)-Fruit-Extract,Rosmarinus-Officinalis-(Rosemary)-Leaf-Extract,Hydroxymethoxyphenyl-Decanone,Bht

Key Ingredients

Retinol,Squalane

Ingredients Details

Bht

Common Name(s): Bht

DESCRIPTION

What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.

Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.

How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ€” enzymes, receptors, structural proteins, or signaling molecules โ€” triggering beneficial biological responses.

Typically Found In: Serums,treatments,moisturizers,specialty products

TECHNICAL DETAILS

Primary Category: Specialty actives

Secondary Functions: Skin-conditioning,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01โ€“5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Specialty active ingredient; check individual sourcing for vegan status.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides

Avoid Combining With: Incompatible with oxidizing agents; check ph stability

SCIENTIFIC NOTE

Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

Retinol

Common Name(s): Vitamin a,all-trans retinol,(all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

CAS Number: 68-26-8

DESCRIPTION

What It Does: Retinol accelerates skin cell turnover, stimulates collagen production, reduces fine lines and wrinkles, fades hyperpigmentation, and helps normalize pore size.

Why It's Used: It is the most evidence-backed anti-aging ingredient available without a prescription. it provides comprehensive skin renewal benefits that no other single cosmetic ingredient can match.

How It Works: Retinol is converted in the skin to retinoic acid, which binds to retinoid receptors in cell nuclei. this activates gene expression changes that accelerate cell turnover, boost collagen synthesis, and inhibit matrix metalloproteinases (collagen-degrading enzymes).

Typically Found In: Night creams,serums,eye creams,targeted treatment products,anti-aging formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ vitamin a derivative

Secondary Functions: Exfoliating,anti-acne,brightening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.025%โ€“1% (otc); start at low concentrations and build up slowly

SOURCING & ETHICS

Vegan Status: Conditional โ€“ can be animal-derived (fish liver, egg yolk) or synthetic; verify source

Halal Status: Conditional โ€“ verify source; synthetic retinol is halal

Source Notes: Cosmetic retinol is predominantly synthetically manufactured. some natural sources include fish liver oils. synthetic is preferred for purity and sustainability.

SKIN COMPATIBILITY

Irritancy Rating: 3/5 โ€“ moderate; can cause dryness, peeling, redness, especially during adjustment period (retinization)

Comedogenicity Rating: 0/5 โ€“ non-comedogenic; actually helps clear pores

Sensitivity Concerns: Retinization period: 2โ€“6 weeks of potential dryness, flaking, and sensitivity. photosensitizing โ€“ must use spf when using retinol. avoid during pregnancy.

Safe for Sensitive Skin: Use with caution โ€“ start at 0.025%, buffer with moisturizer, use every 2โ€“3 nights initially

SAFETY & COMPATIBILITY

Safety Profile: Safe for general use at otc concentrations. not recommended during pregnancy. avoid with waxing. use spf daily. ewg hazard score: varies by concentration.

Works Well With: Niacinamide (soothes irritation),peptides,ceramides,hyaluronic acid,spf (mandatory)

Avoid Combining With: Benzoyl peroxide (may inactivate retinol),ahas/bhas (when new to retinol โ€“ overexfoliation risk),vitamin c (use at different times)

SCIENTIFIC NOTE

Retinol is approximately 20 times less potent than prescription tretinoin (retinoic acid) but significantly better tolerated. the conversion rate of retinol to retinoic acid in skin is the rate-limiting step in its efficacy.

Last Verified: Cosing database,cir safety assessment,journal of investigative dermatology,kligman et al. studies

Primary Sources: 2026-03-12

Squalane

Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane

CAS Number: 0111-01-03

DESCRIPTION

What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.

Why It's Used: The most skin-compatible emollient โ€“ chemically identical to human sebum squalene component with outstanding tolerability across all skin types.

How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.

Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ emollient

Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“100%

SOURCING & ETHICS

Vegan Status: Conditional โ€“ plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out

Halal Status: Yes โ€“ plant-derived

Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Squalene constitutes approximately 12-15% of human sebum โ€“ the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.

Last Verified: Cosing database,huang et al. squalane review,cir safety assessment

Primary Sources: 2026-03-12