
Highlights
WHAT IS IT?
Solution with high concentration of Argireline 10%
FEATURES
Targets dynamic forehead, 'eleven eye', and smile lines; lightweight; smooths skin
BEST FOR
normal
CHECKS
Preservative-free (contains Potassium Sorbate and Phenoxyethanol), Fragrance-free (not mentioned), Silicone-free (not mentioned), Alcohol-free (not mentioned)
Who Is It For?
Adults (age Not Specified) All GendersWhat Does It Help With?
Dynamic Wrinkles Smile Lines Facial RelaxationBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What The Ordinary Says
Product Description:
Argireline Solution 10% offers an advanced formula targeting dynamic forehead, “eleven eye”, and smile lines in an effective, “non-injective” way. By incorporating a high concentration of Argireline™, this lightweight serum improves the appearance of facial areas prone to deep-set lines, resulting in smoother, more relaxed skin.
About the Brand:
Ingredients Overview
Ingredients List
Aqua-(Water),Propanediol,Acetyl-Hexapeptide-8,Trisodium-Ethylenediamine-Disuccinate,Gellan-Gum,Sodium-Chloride,Isoceteth-20,Dimethyl-Isosorbide,Potassium-Sorbate,Phenoxyethanol,Chlorphenesin
Key Ingredients
Acetyl Hexapeptide-8
Ingredients Details
Chlorphenesin
Common Name(s): 3-(4-chlorophenoxy)-1,2-propanediol,globacid
CAS Number: 104-29-0
DESCRIPTION
What It Does: Provides gram-negative focused preservation complementary to phenoxyethanol for comprehensive spectrum coverage.
Why It's Used: Phenoxyethanol complement — chlorphenesin's gram-negative and antifungal coverage complements phenoxyethanol's gram-positive activity for full-spectrum preservation at lower individual concentrations.
How It Works: 4-chlorophenol ether glycol disrupts bacterial and fungal membranes. strong gram-negative activity (pseudomonas, e. coli). good candida antifungal activity. used with phenoxyethanol for synergistic broad-spectrum coverage. ph stable 3-9.
Typically Found In: Comprehensive preservation systems,baby products (low concentration)
TECHNICAL DETAILS
Primary Category: Functional ingredient – glycerol ether preservative
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–0.3%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Eu max 0.3% cosmetics. good safety profile. synergistic combination with phenoxyethanol (0.3% pe + 0.1% chlorphenesin often equivalent to 1% pe alone).
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Chlorphenesin + phenoxyethanol synergy operates through a classic spectrum-filling combination: phenoxyethanol provides strong gram-positive antimicrobial activity while chlorphenesin provides gram-negative and antifungal coverage. the combination's minimum inhibitory concentration sum is subadditive (provides equivalent preservation at combined concentrations below what either alone would require) — textbook pharmacological synergy enabling lower total preservative load.
Last Verified: Cosing database,eu preservative annex v,cir safety assessment
Primary Sources: 2026-03-12
Isoceteth-20
Common Name(s): Isoceteth-20,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function at recommended use concentration.
Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.
How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient – cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Isoceteth-20 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.
Last Verified: Cosing database,isoceteth-20 technical literature
Primary Sources: 2026-03-12
Phenoxyethanol
Common Name(s): 2-phenoxyethanol,rose ether,ethylene glycol monophenyl ether
CAS Number: 122-99-6
DESCRIPTION
What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.
Why It's Used: The benchmark cosmetic preservative – eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.
How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.
Typically Found In: All cosmetic formulations as primary preservative
TECHNICAL DETAILS
Primary Category: Functional ingredient – broad-spectrum preservative
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–1% (eu max 1%)
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at ≤1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations – a consumer perception issue rather than a scientific safety concern.
Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment
Primary Sources: 2026-03-12
Propanediol
Common Name(s): 1,3-propanediol,zemea,bio-propanediol
CAS Number: 504-63-2
DESCRIPTION
What It Does: Provides humectant and solvent functionality from sustainable corn-based fermentation.
Why It's Used: Bio-based propylene glycol alternative from renewable corn — propanediol provides equivalent functionality to propylene glycol with sustainable renewable feedstock and superior skin feel.
How It Works: Two oh groups provide humectant water binding. excellent solvent for fragrances, actives, and preservatives. mild antimicrobial from diol structure for preservative system boosting. renew corn fermentation origin (dupont zemea process). better skin feel than propylene glycol — less sticky.
Typically Found In: Virtually all cosmetic categories as pg alternative
TECHNICAL DETAILS
Primary Category: Functional ingredient – humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–20%
SOURCING & ETHICS
Vegan Status: Yes – from corn sugar fermentation
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Propanediol's dupont tate & lyle bio products 'zemea' process ferments corn sugar to 1,3-propanediol using engineered e. coli — one of the first commercially viable bio-fermentation routes to a cosmetic diol previously made only from petroleum. the renewable route produces chemically identical 1,3-propanediol while reducing carbon footprint by approximately 40% vs petrochemical synthesis.
Last Verified: Cosing database,dupont tate & lyle zemea technical data,cir safety assessment
Primary Sources: 2026-03-12