Shiseido
Shiseido Adenovital Advanced Scalp Essence 480ml
A high-quality hair growth care product born from cutting-edge bioscience and professional ideas. The active ingredient penetrates and transmits a hair growth signal to the hair roots. It promotes hair growth while preventing thinning and hair loss, and grows healthy and firm hair.
Paraben-free
Color-safe
Silicone-free
Thinning
Hair Loss
Fine
Optimized for Your Environment & Lifestyle
Nykaa
In stock
Recommended
Shiseido Adenovital Advanced Scalp Essence 480ml
Shiseido
shiseido-adenovital-advanced-scalp-essence-480ml
Scalp Treatment
10523356004645
Morning or Evening?
How often will you use this product?
Notes
Secure payment protection
Your Biodata Compatibility Analysis
Based on your 6 hair health indices and environmental factors
Poor Match
Significant incompatibilities
Growth Cycle Health Index
Hair Match
Hair Health Index Alignment
Optimal for OSI, SSI, DI, HSI
Ingredient Efficacy
Matching Ingredient Score
Environment Compatibility
Current UV, Air Quality & Humidity
Why This Works for Your Specific Profile
Damage Index:
Damage levels outside specified range may not benefit optimally from product formulation
Water Quality:
No scalp sensitivity-specific conflicts
Hair:
No porosity-specific conflicts
Active Lifestyle:
Activity levels outside optimal range affect product performance and maintenance requirements
Your Hair Profile Integration
Your Hair Archetype
Density Level
Washing Frequency
Shedding Level
Oil Level
Your Hair Health Indices
Oil Secretion (OSI)
Very low oil production
Scalp Sensitivity (SSI)
Very low sensitivity
Growth Rate (CMR)
Poor metabolism rate
Damage Index (DI)
Minimal damage
Hair Strength (HSI)
Very weak strength
Softness Index (SI)
Significant improvement needed
Water & Environmental Integration
Water:
Expected Results & Timeline
Key Highlights
What is it?
Scalp treatment with multiple ingredients
Who Is It For
Adults
Budget
$156.36 - $312.72
Timeline
Why Youโll Love It
What Does It Help With?
Hair loss, Thinning hair, Itching, Dry dandruff, Odor elimination
Best for
Thinning hair
Features
Contains Adenosine, a famous remedy for hair loss and baldness; Works to make hair thicker, denser, and grow faster; Reduces gray hair and promotes hair density and volume; Concentrated scalp treatment for hair loss due to diseases, childbirth, and age-related hair loss; Relieves itching, dry dandruff, and eliminates odor from hair; Contains adenosine, extracts of various plants, vitamin E, and menthol; Does not contain ethyl alcohol
Checks
Ingredients Overview
Ingredients List
adenosine, prickly-steel-extract, arnica-extract, perilla-extract, japanese-pepper-extract, hops-extract, sofora-extract, ginseng-extract, vitamin-e, menthol
Key Ingredients
adenosine, prickly-steel-extract, arnica-extract, perilla-extract, japanese-pepper-extract, hops-extract, sofora-extract, ginseng-extract, vitamin-e, menthol
Ingredients Details
Adenosine
Common Name(s): Adenine riboside,9-beta-d-ribofuranosyladenine
CAS Number: 58-61-7
DESCRIPTION
What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.
Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.
How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.
Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare
TECHNICAL DETAILS
Primary Category: Active ingredient โ purine nucleoside / anti-aging
Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.04%โ0.1%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.
Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph
Primary Sources: 2026-03-12
Adenosine
Common Name(s): Adenine riboside,9-beta-d-ribofuranosyladenine
CAS Number: 58-61-7
DESCRIPTION
What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.
Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.
How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.
Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare
TECHNICAL DETAILS
Primary Category: Active ingredient โ purine nucleoside / anti-aging
Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.04%โ0.1%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.
Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph
Primary Sources: 2026-03-12
Menthol
Common Name(s): L-menthol,peppermint camphor,(-)-menthol
CAS Number: 89-78-1
DESCRIPTION
What It Does: Activates trpm8 cold thermoreceptors for intense cooling sensation and analgesic activity.
Why It's Used: The most potent cosmetic cooling agent โ direct trpm8 agonist providing cooling sensation without actual temperature reduction for refreshing and analgesic formulations.
How It Works: Potent trpm8 (menthol receptor/cold thermosensor) agonist โ activation at room temperature mimics cold sensation without actual cooling. anti-pruritic via trpm8 activation competing with itch c-fiber signaling. antimicrobial via membrane disruption.
Typically Found In: Cooling products,scalp treatments,oral care,pain relief,foot care,after-sun
TECHNICAL DETAILS
Primary Category: Active ingredient โ cooling sensory terpenoid
Secondary Functions: Redness reduction,anti-inflammatory,calming
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ from mentha piperita or synthetic
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 โ low to moderate; potential sensitizer
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.
Safe for Sensitive Skin: Avoid near eyes. use with caution at concentrations above 1% for sensitive skin.
SAFETY & COMPATIBILITY
Safety Profile: Eu max 4.5% (leave-on); regulations vary by application site. avoid on infants' face.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Menthol's exceptional cooling potency stems from its ec50 for trpm8 activation of approximately 10ฮผm (vs camphor's ec50 of ~5mm โ 500ร lower potency). this 500ร potency advantage explains why even tiny concentrations of menthol provide intense cooling, while much higher concentrations of camphor are required for equivalent sensation.
Last Verified: Cosing database,mckemy et al. menthol trpm8 discovery,cir safety assessment
Primary Sources: 2026-03-12
Menthol
Common Name(s): L-menthol,peppermint camphor,(-)-menthol
CAS Number: 89-78-1
DESCRIPTION
What It Does: Activates trpm8 cold thermoreceptors for intense cooling sensation and analgesic activity.
Why It's Used: The most potent cosmetic cooling agent โ direct trpm8 agonist providing cooling sensation without actual temperature reduction for refreshing and analgesic formulations.
How It Works: Potent trpm8 (menthol receptor/cold thermosensor) agonist โ activation at room temperature mimics cold sensation without actual cooling. anti-pruritic via trpm8 activation competing with itch c-fiber signaling. antimicrobial via membrane disruption.
Typically Found In: Cooling products,scalp treatments,oral care,pain relief,foot care,after-sun
TECHNICAL DETAILS
Primary Category: Active ingredient โ cooling sensory terpenoid
Secondary Functions: Redness reduction,anti-inflammatory,calming
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ from mentha piperita or synthetic
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 โ low to moderate; potential sensitizer
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.
Safe for Sensitive Skin: Avoid near eyes. use with caution at concentrations above 1% for sensitive skin.
SAFETY & COMPATIBILITY
Safety Profile: Eu max 4.5% (leave-on); regulations vary by application site. avoid on infants' face.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Menthol's exceptional cooling potency stems from its ec50 for trpm8 activation of approximately 10ฮผm (vs camphor's ec50 of ~5mm โ 500ร lower potency). this 500ร potency advantage explains why even tiny concentrations of menthol provide intense cooling, while much higher concentrations of camphor are required for equivalent sensation.
Last Verified: Cosing database,mckemy et al. menthol trpm8 discovery,cir safety assessment
Primary Sources: 2026-03-12
Personalized Usage Instructions
How to Use
Step 1
After washing your hair, wipe off the water well, or use it on your dry scalp
Step 2
Apply the tip of the nozzle directly to the scalp while spraying, and apply it with the pad of your finger
Step 3
By massaging when using, it promotes blood circulation and supports hair growth
Medical Chemicals
Protein/Moisture
- Protein/Moisture balance
pH Level
- Acidic
Porosity Taget
- Normal Porosity
Customized for Your Profile
Scalp Condtions
Anti-Dandruff, Sensitive Scalp, pH Balanced, Oil Control, Dry Scalp
Climate Suitability
Humid, Dry, Hard Water, Soft Water, UV Protection, Pollution Shield, Winter, Summer
Clinical Claims
Frequency
After washing your hair, wipe off the water well, or use it on your dry scalp. Apply the tip of the nozzle directly to the scalp while spraying, and apply it with the pad of your finger. By massaging when using, it promotes blood circulation and supports hair growth.
