SheaMoisture Manuka Honey & Yogurt Hydrate + Repair Multi-Action Leave-In

DESCRIPTION

What It Does: Provides antioxidant protection from reactive oxygen species, reduces inflammatory cytokine production in skin, and conditions skin surface through the plant's secondary metabolite complex.

Why It's Used: Chosen for its natural origin narrative, traditional use heritage, and multi-functional phytochemical profile that supports several concurrent skin care claims from one ingredient.

How It Works: Polyphenols, terpenoids, and alkaloids in the oil scavenge ros via hydrogen atom transfer, inhibit nf-kb or cox-2 inflammatory pathways, and interact with skin surface proteins for conditioning.

Typically Found In: Botanical skin care,natural products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Plant secondary metabolites evolved as uv photoprotectants and antimicrobial agents — mechanisms that directly translate to cosmetic antioxidant and anti-inflammatory activity in human skin.

Last Verified: Cosing database,adansonia digitata seed oil botanical review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Prevents microbial contamination that would otherwise render water-containing cosmetics unsafe — inhibiting bacterial, fungal, and yeast growth through membrane disruption, enzyme inhibition, or metabolic interference at permitted regulatory concentrations.

Why It's Used: Preservatives are safety-critical — un-preserved water-containing cosmetics can develop dangerous microbial contamination (pseudomonas aeruginosa eye infections, s. aureus skin infections) within days. preservation is a regulatory requirement, not an optional enhancement.

How It Works: Mechanism varies by class: organic acids (benzoic, dehydroacetic) disrupt intracellular ph in bacteria and fungi by proton flux across membranes; parabens inhibit membrane-associated enzyme function; chlorhexidine disrupts bacterial and fungal membrane integrity through divalent ion chelation of membrane phospholipids.

Typically Found In: All aqueous formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Check annex v eu limits

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Eu regulation 1223/2009 annex v lists all permitted preservatives with maximum concentrations — preservatives not listed are prohibited. formulators must verify both permitted status and maximum concentration for each market before finalising preservation systems.

Last Verified: Eu regulation 1223/2009 annex v,cosmetic preservative regulatory review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Reduces skin inflammation, soothes irritation, promotes wound healing, and enhances penetration of co-formulated actives.

Why It's Used: Premium natural soothing active with combined anti-inflammatory, wound healing, and penetration-enhancing activity – clinically validated across sensitive, reactive, and irritated skin types.

How It Works: Inhibits nf-kb pathway reducing pro-inflammatory cytokines il-1β, il-6, tnf-α. enhances stratum corneum lipid fluidity increasing penetration of co-delivered actives. antimicrobial against s. aureus and c. albicans. promotes keratinocyte migration for wound healing.

Typically Found In: Sensitive skin products,post-procedure formulations,anti-irritant formulas,wound healing

TECHNICAL DETAILS

Primary Category: Active ingredient – soothing / anti-inflammatory

Secondary Functions: Anti-inflammatory,penetration enhancement,antimicrobial

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Yes – from candeia tree (vanillosmopsis erythropappa) or synthetic

Halal Status: Yes

Source Notes: Natural (-)-alpha-bisabolol from brazilian candeia tree is more sustainable and potent than chamomile-derived bisabolol. synthetic (±)-bisabolol is racemic with slightly lower anti-inflammatory potency.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Bisabolol's dual function as both an anti-inflammatory and a penetration enhancer is synergistic – by reducing the inflammatory response that increases barrier tightness while simultaneously fluidizing stratum corneum lipids, it provides enhanced delivery of co-formulated actives in the very conditions where delivery is most needed.

Last Verified: Cosing database,piazza et al. bisabolol anti-inflammatory study,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Softens and conditions skin by integrating into sc lipid bilayers, delivers essential fatty acids (oleic, linoleic, linolenic) for barrier lipid synthesis, and provides rich, non-stripping moisturisation.

Why It's Used: Natural carrier oils provide the closest compositional match to endogenous sc lipids, delivering emolliency through genuine barrier integration rather than simple surface occlusion.

How It Works: Fatty acid triglycerides partition into sc lipid bilayers — oleic acid (c18:1) provides fluid, emollient integration; linoleic acid (c18:2) acts as essential ceramide precursor; saturated fatty acids provide more occlusive barrier reinforcement.

Typically Found In: Moisturisers,facial oils,natural skin care

TECHNICAL DETAILS

Primary Category: Functional ingredient – emollient

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–100%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Essential fatty acids — linoleic (c18:2, n-6) and α-linolenic (c18:3, n-3) acids — cannot be synthesised by the body; topical delivery through carrier oils provides direct substrate for ceramide and eicosanoid biosynthesis in the epidermis.

Last Verified: Cosing database,butyrospermum parkii butter carrier oil botanical review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Lightweight, stable emollient that solubilizes oil-soluble actives for excellent delivery without greasy feel.

Why It's Used: Universal lightweight emollient base and solubilizer for oil-soluble actives in serums and low-viscosity formulations where mineral oil or petrolatum would be too heavy.

How It Works: Medium-chain length provides ideal balance of spreading coefficient, penetration rate, and barrier-sealing properties. excellent solubilizer for vitamin e, retinoids, and other lipophilic actives.

Typically Found In: Serums,facial oils,sunscreens,anti-aging products,hair products

TECHNICAL DETAILS

Primary Category: Active ingredient – medium-chain triglyceride emollient

Secondary Functions: Active solubilizer,spreading agent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–50%

SOURCING & ETHICS

Vegan Status: Yes – from coconut/palm kernel oil

Halal Status: Yes

Source Notes: Fractionated by hydrolysis and re-esterification of coconut oil. only c8 and c10 fatty acids retained.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – very low; medium-chain length generally non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mct oil's medium-chain length (c8/c10) provides superior oxidative stability vs longer polyunsaturated chains and better skin aesthetics (lighter, less greasy) vs longer chain emollients (c16/c18). excellent solubilizer for retinoic acid, tocopheryl esters, and other lipophilic actives.

Last Verified: Cosing database,cir safety assessment,ewg skin deep

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the most potent antimicrobial diol activity alongside skin feel enhancement.

Why It's Used: Premium antimicrobial diol — caprylyl glycol's c8 chain provides the strongest membrane-disrupting antimicrobial activity of common diol preservative boosters with unique skin-feel enhancement.

How It Works: C8 1,2-diol: c8 chain length provides strongest bacterial and fungal membrane disruption of common diols. emollient skin feel improvement from c8 chain length interaction with skin surface. active at lower concentrations than shorter-chain diols. synergistic with ethylhexylglycerin.

Typically Found In: Natural preservation systems,skin feel enhancement

TECHNICAL DETAILS

Primary Category: Functional ingredient – antimicrobial humectant

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Caprylyl glycol's antimicrobial potency follows the chain-length dependent membrane activity of fatty acids: c8 is the optimal chain length for membrane disruption (same as caprylic acid's antimicrobial optimum), providing maximum membrane integration without the skin sensitisation associated with longer chain lengths. this chain-length pharmacophore relationship is why c8 > c6 > c5 in diol antimicrobial potency despite identical head group chemistry.

Last Verified: Cosing database,schülke sensiva sc 50 technical data,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Cetrimonium chloride has an established safety profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,cetrimonium chloride technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides c16 fatty alcohol emolliency and thickening for well-textured cosmetic emulsions.

Why It's Used: Lighter-textured fatty alcohol alternative to stearyl alcohol for creams and conditioners requiring less heavy emolliency.

How It Works: C16 chain length provides slightly lower melting point (49°c) than stearyl (60°c) giving softer, lighter emulsion texture. forms lamellar networks for thickening and stability. direct skin and hair conditioning via fatty alcohol film.

Typically Found In: Creams,hair conditioners,lotions

TECHNICAL DETAILS

Primary Category: Functional ingredient – fatty alcohol

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–15%

SOURCING & ETHICS

Vegan Status: Yes – from vegetable or coconut/palm fatty acids

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Cetyl alcohol's c16 chain length is at the approximate thermal transition point for fatty alcohol lamellar crystallization at skin temperature (33°c). this transition (from ordered crystalline to disordered liquid phase near skin temperature) provides the characteristic 'melts on application' sensory profile that makes cetyl alcohol-containing products feel cooling and light on initial application.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the complete fragrance profile contributing to product sensory experience and consumer appeal.

Why It's Used: Fragrance is a major consumer purchase driver — up to 70% of consumers make purchasing decisions partially based on product scent.

How It Works: Fragrance blends interact with olfactory receptors providing the sensory profile — complex mixtures activate multiple receptor types for rich, multidimensional scent experiences.

Typically Found In: All fragrance products

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Standard use levels

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ifra guidelines set usage limits for fragrance ingredients based on skin sensitisation and phototoxicity assessment for each application category.

Last Verified: Eu regulation 1223/2009 annex iii,ifra standards,fragrance allergen declaration requirements

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12