Sensibio Mask

DESCRIPTION

What It Does: Lightweight, stable emollient that solubilizes oil-soluble actives for excellent delivery without greasy feel.

Why It's Used: Universal lightweight emollient base and solubilizer for oil-soluble actives in serums and low-viscosity formulations where mineral oil or petrolatum would be too heavy.

How It Works: Medium-chain length provides ideal balance of spreading coefficient, penetration rate, and barrier-sealing properties. excellent solubilizer for vitamin e, retinoids, and other lipophilic actives.

Typically Found In: Serums,facial oils,sunscreens,anti-aging products,hair products

TECHNICAL DETAILS

Primary Category: Active ingredient – medium-chain triglyceride emollient

Secondary Functions: Active solubilizer,spreading agent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–50%

SOURCING & ETHICS

Vegan Status: Yes – from coconut/palm kernel oil

Halal Status: Yes

Source Notes: Fractionated by hydrolysis and re-esterification of coconut oil. only c8 and c10 fatty acids retained.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – very low; medium-chain length generally non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mct oil's medium-chain length (c8/c10) provides superior oxidative stability vs longer polyunsaturated chains and better skin aesthetics (lighter, less greasy) vs longer chain emollients (c16/c18). excellent solubilizer for retinoic acid, tocopheryl esters, and other lipophilic actives.

Last Verified: Cosing database,cir safety assessment,ewg skin deep

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides light silky emolliency combining isononanoate lightness with cetearyl conditioning.

Why It's Used: Light conditioning ester — uniquely combines the lightness of branched-acid esters with the skin conditioning of fatty alcohol esters in one ingredient, providing both feel attributes simultaneously.

How It Works: Cetearyl alcohol (c16+c18) + isononanoic acid (3,5,5-trimethylhexanoic) ester. light feel: branched acid. conditioning: cetearyl component. non-greasy. cosmos accepted. crodamol sts: commercial reference.

Typically Found In: Light emollient serums,skin care,body lotion

TECHNICAL DETAILS

Primary Category: Functional ingredient – emollient

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–20%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Cetearyl isononanoate's dual feel profile from two molecular components: isononanoate acid branching provides lightness (prevents ordered surface film); cetearyl alcohol provides conditioning (long-chain skin interaction). same ester linkage delivering both properties — emollient design combining complementary components.

Last Verified: Cosing database,crodamol sts technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides rapid-acting prebiotic microbiome support with humectant conditioning from short-chain fructan oligomers.

Why It's Used: Fast-acting prebiotic for rapid microbiome support — fos's shorter chain length provides faster fermentation by beneficial bacteria vs long-chain inulin, enabling quicker microbiome compositional shifts.

How It Works: Dp 2-10 fructooligomers (vs inulin's dp 10-60) provide more rapid access to bacterial fermentation enzymes. higher water solubility and humectant activity than long-chain inulin. more bioavailable to skin surface bacteria vs longer-chain inulin that penetrates deeper before fermentation.

Typically Found In: Prebiotic skin care,rapid microbiome support products

TECHNICAL DETAILS

Primary Category: Active ingredient – short-chain prebiotic

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–5%

SOURCING & ETHICS

Vegan Status: Yes – from sucrose enzymatic synthesis or inulin hydrolysis

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Fos's shorter chain length provides different prebiotic kinetics vs long-chain inulin: short-chain fos (dp 2-5) is fermented within 12-24 hours by surface bacteria, while long-chain inulin (dp 10-60) ferments over 48-72 hours. this temporal difference enables formulation of 'fast-acting' (fos) vs 'sustained-release' (inulin) prebiotic products with different microbiome support kinetics.

Last Verified: Cosing database,roberfroid fos prebiotic review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides emollient skin conditioning with spreading value determined by the acid-alcohol ester molecular components.

Why It's Used: Glycol palmitate is selected for its c16 palmitic ester — the c-chain length provides biomimetic emolliency matching the dominant sc ceramide fatty acid, which distinguishes glycol palmitate from esters of adjacent chain lengths in the same polarity tier.

How It Works: Ester polarity controls spreading: branched short-chain fast dry; medium moderate spreading; long occlusive. ester c=o provides polar adhesion to skin.

Typically Found In: Cosmetic formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Safety documented in cosing at standard formulation concentrations.

Last Verified: Cosing database,glycol palmitate technical review

Primary Sources: 2026-03-22

DESCRIPTION

What It Does: Provides ultra-lightweight dry-touch emolliency with excellent pigment dispersion for lightweight formulations.

Why It's Used: Premium lightweight emollient for dry-touch formulations — isohexadecane's highly branched structure provides the lightest, driest application feel of common cosmetic hydrocarbons.

How It Works: Highly branched c16 isoparaffin provides very low surface tension for fast spreading. completely non-polar structure provides no water retention (dry feel). excellent pigment wetting for colour cosmetics. very low viscosity (2.5 cst) for fluid application.

Typically Found In: Lightweight foundations,sunscreens,colour cosmetics,dry-touch products

TECHNICAL DETAILS

Primary Category: Functional ingredient – branched hydrocarbon emollient

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30%

SOURCING & ETHICS

Vegan Status: Yes – synthetic hydrocarbon

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Isohexadecane's highly branched structure (methyl-substituted hexadecane) prevents the close molecular packing that creates liquid crystalline phases in linear hydrocarbons, resulting in a permanently disordered liquid state with very low viscosity and surface tension. this structural disorder from branching is the molecular basis for the lighter, faster-spreading application feel vs equivalent linear hydrocarbons.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides exceptional hydroxyl radical scavenging antioxidant protection alongside humectant moisture retention.

Why It's Used: Used for potent hydroxyl radical scavenging where standard antioxidants (tocopherol, ascorbic acid) are less effective, combined with humectant activity.

How It Works: 6 hydroxyl groups provide both water binding (humectant) and direct hydroxyl radical (.oh) scavenging. hydroxyl radicals are the most reactive and damaging free radicals – mannitol is one of few compounds that scavenges them directly.

Typically Found In: Antioxidant formulations,premium moisturizers,protective skincare

TECHNICAL DETAILS

Primary Category: Functional ingredient – sugar alcohol / free radical scavenger

Secondary Functions: Free radical scavenger,superior antioxidant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – plant-derived or synthetic

Halal Status: Yes

Source Notes: Plant-derived from ash tree manna, seaweed, mushrooms, or produced by reduction of mannose. gras food-approved.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mannitol's rate constant for hydroxyl radical scavenging (k = 1.4 × 10^7 m^-1s^-1) makes it one of the most effective biological hydroxyl radical scavengers. this is important because hydroxyl radicals cannot be scavenged by standard antioxidants like tocopherol or ascorbic acid.

Last Verified: Cosing database,halliwell et al. free radical scavenging,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.

Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.

How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix — enzymes, receptors, structural proteins, or signaling molecules — triggering beneficial biological responses.

Typically Found In: Serums,treatments,moisturizers,specialty products

TECHNICAL DETAILS

Primary Category: Specialty actives

Secondary Functions: Skin-conditioning,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Specialty active ingredient; check individual sourcing for vegan status.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides

Avoid Combining With: Incompatible with oxidizing agents; check ph stability

SCIENTIFIC NOTE

Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-γ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15