
Highlights
WHAT IS IT?
Overnight acne and dark spots drying lotion with multiple key ingredients
FEATURES
Fast-acting formula, Suitable for all skin types and tones, Effective for oily and dry skin, Relieves discomfort from inflamed acne
BEST FOR
sensitive
CHECKS
Does not contain fragrance-free, silicone-free, PEG-free, alcohol-free, aluminum-free, microplastic-free, oil-free, sulfate-free, paraben-free, fungal-acne safe, EU allergen free, preservative free (however contains DMDM hydantoin and methylchloroisothiazolinone/methylisothiazolinone which are preservatives)
Who Is It For?
Adults All GendersWhat Does It Help With?
Acne Dark Spots Blackheads Whiteheads Inflamed And Painful ZitsBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Sanfe Says
Product Description:
Sanfe Overnight Acne & Dark Spots Drying Lotion delivers rapid results with its powerful formula designed to clarify skin and target breakouts, blackheads, and whiteheads. Suitable for all skin types and tones, this versatile treatment works overnight to address acne caused by excess sebum or dryness. It not only alleviates discomfort from painful, inflamed zits but also shows visible improvement after just one use. Experience clearer, smoother skin with this effective 10ml solution.
About the Brand:
Ingredients Overview
Ingredients List
aqua,glycerine,propylene-glycol,colloidal-sulfide,isopropyl-alcohol,calamine,salicylic-acid,zinc-oxide-(nano),k-150,camphor,titanium-dioxide,edta,dmdm-hydantoin-(and)-methylchloroisothiazolinone-(and)-methylisothiazolinone
Key Ingredients
salicylic-acid,zinc-oxide,calamine,camphor
Ingredients Details
Calamine
Common Name(s): Calamine,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function at recommended use concentration.
Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.
How It Works: Works through the mechanism of its molecular class as documented in peer-reviewed cosmetic literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Calamine has an established safety profile within the cosmetic regulatory framework at standard use concentrations.
Last Verified: Cosing database,calamine technical literature
Primary Sources: 2026-03-12
Camphor
Common Name(s): 2-bornanone,2-camphanone,gum camphor
CAS Number: 76-22-2
DESCRIPTION
What It Does: Provides cooling sensation, analgesic, and anti-itch activity through trpm8 and trpv1 modulation.
Why It's Used: Cooling-sensation active with topical analgesic and anti-itch benefits for soothing formulations requiring temperature-sensation modification.
How It Works: Activates trpm8 (cold thermoreceptor) for cooling sensation. at higher concentrations, desensitizes trpv1 (heat/pain receptor) for analgesic activity. penetration enhancement via stratum corneum lipid fluidization. antimicrobial via membrane disruption.
Typically Found In: Cooling balms,topical pain relief,anti-itch products,sensory skincare
TECHNICAL DETAILS
Primary Category: Active ingredient โ monoterpenoid sensory active
Secondary Functions: Redness reduction,anti-inflammatory,calming
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%โ3%
SOURCING & ETHICS
Vegan Status: Yes โ from cinnamomum camphora or synthetic
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 โ low to moderate at high concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Avoid contact with eyes. can cause skin sensitization at concentrations above eu limit. contraindicated in infants and young children.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Eu max 1.5% (leave-on body). avoid near eyes. do not apply to broken skin. not for infant use near face.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Camphor's concurrent activation of trpm8 (cooling) and desensitization of trpv1 (heat/pain) provides a unique dual sensory modulation that both masks pain (trpv1 desensitization) and replaces it with a pleasant cooling sensation (trpm8 activation) โ explaining the well-documented analgesic efficacy of camphor-containing topical preparations.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Edta
Common Name(s): Edta,inci ingredient,cosmetic active
CAS Number: N/a
DESCRIPTION
What It Does: Provides documented cosmetic activity from edta.
Why It's Used: Edta delivers formulation value through its specific biological activity and established safety and efficacy.
How It Works: Source: edta. mechanism: documented in cosmetic literature. safety: cosing-reviewed. standard cosmetic use concentrations.
Typically Found In: Skin care formulations,active products
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ5%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Edta provides cosmetic activity through its characteristic mechanism. at standard concentrations it delivers documented biological activity with an established safety profile from cosmetic science literature and regulatory review.
Last Verified: Cosing database,edta technical literature
Primary Sources: 2026-03-12
Glycerine
Common Name(s): Glycerin,universal humectant,water-binding skin conditioning
CAS Number: N/a
DESCRIPTION
What It Does: Attracts and retains moisture in the sc, improves skin barrier function at low concentrations, provides gentle keratolytic softening, and acts as a co-solvent for water-soluble actives.
Why It's Used: The reference humectant โ lowest cost, best safety profile, universal formulation compatibility, and present naturally in the sc via lipase-mediated glycerolipid hydrolysis makes glycerin the industry standard against which all humectants are benchmarked.
How It Works: Three hydroxyl groups form 6 h-bonds with water molecules per glycerol unit โ the highest oh-group density per carbon of any commercial humectant. glycerin also down-regulates epidermal serine proteases that overactivate in dry sc, improving desquamation and barrier integrity.
Typically Found In: All cosmetics,universal
TECHNICAL DETAILS
Primary Category: Functional ingredient โ humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ40%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Epidermal lipases hydrolyse sc glycerophospholipids during cornification, releasing glycerol that contributes to the natural nmf โ topical glycerin directly supplements this endogenous sc humectant pool.
Last Verified: Cosing database,glycerin universal humectant review
Primary Sources: 2026-03-12