
Highlights
WHAT IS IT?
Night serum capsules with Retinol and ceramides
FEATURES
Clinically proven to reduce lines and wrinkles in 1 night, delivers firmer skin in 4 weeks, 100% biodegradable capsules, airtight for optimal Retinol freshness
BEST FOR
combination
CHECKS
Fragrance-free, Paraben-free, Lactose-free
Who Is It For?
Ages 18-65+ All GendersWhat Does It Help With?
Wrinkle Reduction Fine Lines Reduction Pore Reduction Skin SmoothingBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What RoC Says
Product Description:
A gentle yet potent overnight face serum for wrinkles and lines formulated with Advanced RoC® Retinol and ceramides.
About the Brand:
Ingredients Overview
Ingredients List
Cyclopentasiloxane, Ethylhexyl Cocoate, Dimethiconol, Glycine Soja (Soybean) Oil, Retinol, Dimethylmethoxy Chromanol, Ceramide NP, Phenoxyethanol.
Key Ingredients
RoC Retinol, ceramides, antioxidants
Ingredients Details
Ceramides
Common Name(s): Ceramides,ceramide sphingolipid,sc barrier lipid
CAS Number: N/a
DESCRIPTION
What It Does: Restores sc lamellar lipid bilayers, reduces trans-epidermal water loss, repairs barrier dysfunction in dry and eczematous skin, and strengthens the physical barrier against environmental irritants.
Why It's Used: Provides direct structural barrier lipid replacement — unlike humectants that attract water, ceramides physically rebuild the lipid bilayer architecture required to retain moisture within the skin.
How It Works: Ceramides integrate into the sc intercellular lamellar bilayer, restoring the ordered orthorhombic packing disrupted in barrier-compromised skin. the sphingosine backbone's amide bond and hydroxyl groups form the h-bonding network that stabilises the lamellar structure.
Typically Found In: Barrier repair,dry skin,eczema-prone
TECHNICAL DETAILS
Primary Category: Functional ingredient – emollient
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%–5%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 1/5 – low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Sc ceramides comprise ~50% of the sc lipid mass (by weight) and are essential for barrier function; ceramide depletion in atopic dermatitis and aged skin is a primary driver of barrier dysfunction and tewl elevation.
Last Verified: Cosing database,ceramides ceramide barrier review
Primary Sources: 2026-03-12
Retinol
Common Name(s): Vitamin a,all-trans retinol,(all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
CAS Number: 68-26-8
DESCRIPTION
What It Does: Retinol accelerates skin cell turnover, stimulates collagen production, reduces fine lines and wrinkles, fades hyperpigmentation, and helps normalize pore size.
Why It's Used: It is the most evidence-backed anti-aging ingredient available without a prescription. it provides comprehensive skin renewal benefits that no other single cosmetic ingredient can match.
How It Works: Retinol is converted in the skin to retinoic acid, which binds to retinoid receptors in cell nuclei. this activates gene expression changes that accelerate cell turnover, boost collagen synthesis, and inhibit matrix metalloproteinases (collagen-degrading enzymes).
Typically Found In: Night creams,serums,eye creams,targeted treatment products,anti-aging formulations
TECHNICAL DETAILS
Primary Category: Active ingredient – vitamin a derivative
Secondary Functions: Exfoliating,anti-acne,brightening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.025%–1% (otc); start at low concentrations and build up slowly
SOURCING & ETHICS
Vegan Status: Conditional – can be animal-derived (fish liver, egg yolk) or synthetic; verify source
Halal Status: Conditional – verify source; synthetic retinol is halal
Source Notes: Cosmetic retinol is predominantly synthetically manufactured. some natural sources include fish liver oils. synthetic is preferred for purity and sustainability.
SKIN COMPATIBILITY
Irritancy Rating: 3/5 – moderate; can cause dryness, peeling, redness, especially during adjustment period (retinization)
Comedogenicity Rating: 0/5 – non-comedogenic; actually helps clear pores
Sensitivity Concerns: Retinization period: 2–6 weeks of potential dryness, flaking, and sensitivity. photosensitizing – must use spf when using retinol. avoid during pregnancy.
Safe for Sensitive Skin: Use with caution – start at 0.025%, buffer with moisturizer, use every 2–3 nights initially
SAFETY & COMPATIBILITY
Safety Profile: Safe for general use at otc concentrations. not recommended during pregnancy. avoid with waxing. use spf daily. ewg hazard score: varies by concentration.
Works Well With: Niacinamide (soothes irritation),peptides,ceramides,hyaluronic acid,spf (mandatory)
Avoid Combining With: Benzoyl peroxide (may inactivate retinol),ahas/bhas (when new to retinol – overexfoliation risk),vitamin c (use at different times)
SCIENTIFIC NOTE
Retinol is approximately 20 times less potent than prescription tretinoin (retinoic acid) but significantly better tolerated. the conversion rate of retinol to retinoic acid in skin is the rate-limiting step in its efficacy.
Last Verified: Cosing database,cir safety assessment,journal of investigative dermatology,kligman et al. studies
Primary Sources: 2026-03-12