Quench Zit Fix Serum With Salicylic Acid & Chia Seeds

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

1-2-hexanediol has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,1-2-hexanediol technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Soothes irritation, accelerates wound healing, promotes skin cell renewal, and provides mild keratolytic exfoliation.

Why It's Used: Gold standard multi-function soothing active – one of the most widely used cosmetic ingredients across all product types for its exceptional tolerability and clinically proven multi-action skin conditioning.

How It Works: Promotes keratinocyte proliferation and fibroblast migration for wound healing. mild keratolytic activity by disrupting corneocyte binding. anti-irritant via direct protein binding and anti-inflammatory cytokine reduction. humectant activity via hydroxyl groups.

Typically Found In: Post-procedure products,sensitive skin formulas,wound care,anti-acne treatments,baby products

TECHNICAL DETAILS

Primary Category: Active ingredient – soothing / anti-inflammatory

Secondary Functions: Wound healing,keratolytic,anti-irritant

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–2%

SOURCING & ETHICS

Vegan Status: Yes – synthetic or comfrey-derived

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Exceptionally well-tolerated; suitable for all skin types including baby and compromised skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Allantoin's keratinocyte proliferation stimulation occurs via receptor-mediated signaling (possibly machr activation) rather than non-specific irritation-driven proliferation, making it a true wound-healing stimulant rather than a pro-inflammatory proliferative signal.

Last Verified: Cosing database,cir safety assessment,araújo et al. allantoin review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Dextrin has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,dextrin technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Glucose has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,glucose technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Stimulates collagen synthesis and wound healing while reducing inflammation – the primary active in centella asiatica's skin repair activity.

Why It's Used: Standardized centella active for precise wound healing, collagen stimulation, and anti-inflammatory dosing with superior consistency vs whole centella extract.

How It Works: Activates tgf-beta1 receptor signaling to upregulate collagen i, iii, and iv synthesis in fibroblasts. inhibits nf-kb for anti-inflammatory activity. promotes keratinocyte migration and proliferation for re-epithelialization. also strengthens lamellar body structures.

Typically Found In: Post-procedure recovery,wound healing serums,anti-aging products,sensitive skin formulas

TECHNICAL DETAILS

Primary Category: Active ingredient – soothing / anti-inflammatory

Secondary Functions: Collagen stimulation,wound healing,anti-inflammatory

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–2%

SOURCING & ETHICS

Vegan Status: Yes – from centella asiatica

Halal Status: Yes

Source Notes: Extracted from centella asiatica aerial parts. standardized to madecassoside content for consistent bioactivity.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Yes – particularly recommended for sensitive skin

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Madecassoside is the most water-soluble and bioavailable of the four major centella triterpene glycosides. its tgf-beta1-mediated collagen stimulation distinguishes it from other soothing actives – providing not just anti-inflammatory relief but active tissue remodeling and collagen neosynthesis.

Last Verified: Cosing database,bylka et al. centella review,liu et al. madecassoside collagen study

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Activates trpm8 cold thermoreceptors for intense cooling sensation and analgesic activity.

Why It's Used: The most potent cosmetic cooling agent – direct trpm8 agonist providing cooling sensation without actual temperature reduction for refreshing and analgesic formulations.

How It Works: Potent trpm8 (menthol receptor/cold thermosensor) agonist – activation at room temperature mimics cold sensation without actual cooling. anti-pruritic via trpm8 activation competing with itch c-fiber signaling. antimicrobial via membrane disruption.

Typically Found In: Cooling products,scalp treatments,oral care,pain relief,foot care,after-sun

TECHNICAL DETAILS

Primary Category: Active ingredient – cooling sensory terpenoid

Secondary Functions: Redness reduction,anti-inflammatory,calming

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–2%

SOURCING & ETHICS

Vegan Status: Yes – from mentha piperita or synthetic

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 2/5 – low to moderate; potential sensitizer

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.

Safe for Sensitive Skin: Avoid near eyes. use with caution at concentrations above 1% for sensitive skin.

SAFETY & COMPATIBILITY

Safety Profile: Eu max 4.5% (leave-on); regulations vary by application site. avoid on infants' face.

Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Menthol's exceptional cooling potency stems from its ec50 for trpm8 activation of approximately 10μm (vs camphor's ec50 of ~5mm – 500× lower potency). this 500× potency advantage explains why even tiny concentrations of menthol provide intense cooling, while much higher concentrations of camphor are required for equivalent sensation.

Last Verified: Cosing database,mckemy et al. menthol trpm8 discovery,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Tocopherol neutralizes free radicals that damage skin cells, protects cell membranes from lipid peroxidation, moisturizes, and helps maintain a healthy skin barrier.

Why It's Used: It is used as both a skin-active antioxidant and a formulation stabilizer (preventing oxidation of other ingredients). it has decades of safety and efficacy evidence and works synergistically with vitamin c.

How It Works: As a chain-breaking antioxidant, tocopherol donates hydrogen atoms to interrupt lipid peroxidation chain reactions. it is regenerated by vitamin c (ascorbic acid) in the vitamins c+e antioxidant cycle, creating a more durable antioxidant defense.

Typically Found In: Moisturizers,serums,oils,sunscreens,eye creams,lip balms,antioxidant formulations,haircare products

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant/vitamin e

Secondary Functions: Emollient,formulation stabilizer,barrier support

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (typical: 0.1–0.5% as active; higher as formulation antioxidant)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (soybean, sunflower, wheat germ oil) or synthetic

Halal Status: Yes – plant-derived or synthetic

Source Notes: Natural d-alpha-tocopherol is derived from plant oils and is more bioactive. synthetic dl-alpha-tocopherol is less expensive. tocopherol acetate (tocopheryl acetate) is the more stable ester form.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; rare contact sensitivity reported

Comedogenicity Rating: 2/5 – mildly comedogenic at higher concentrations; formulation-dependent

Sensitivity Concerns: A small percentage of people report contact sensitization to tocopherol, particularly with leave-on products. comedogenicity risk is higher in oil-heavy formulations.

Safe for Sensitive Skin: Generally yes; perform patch test if history of vitamin e sensitivity

SAFETY & COMPATIBILITY

Safety Profile: Very safe; widely used. ewg hazard score: 2–3 (depending on concentration). no significant systemic concerns from topical use.

Works Well With: Ascorbic acid (vitamin c) – synergistic antioxidant pair,ferulic acid – stabilizes and boosts both c and e,ceramides,spf,retinol

Avoid Combining With: Very high concentrations of benzoyl peroxide may oxidize tocopherol; potential comedogenicity concerns in acne-prone skin when in heavy oil bases

SCIENTIFIC NOTE

The combination of vitamin c, vitamin e, and ferulic acid (the 'ce ferulic' formulation) provides fourfold photoprotection against uv-induced free radical damage – a synergy documented in landmark research by pinnell et al.

Last Verified: Cosing database,cir safety assessment,pinnell et al. (2005) journal of investigative dermatology,efsa panel on food additives

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Trideceth-6 has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,trideceth-6 technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the universal solvent and vehicle for water-soluble actives and the continuous phase of all o/w emulsions.

Why It's Used: The most essential cosmetic ingredient — aqua (water) is listed first on virtually all water-containing cosmetic inci labels as the highest-concentration ingredient, serving as the foundation of the global cosmetics industry.

How It Works: Acts as solvent for all water-soluble ingredients (glycols, amino acids, water-soluble actives). forms the continuous external phase of o/w emulsions (lotions, creams, serums). provides aqueous environment for enzymatic and chemical reactions between actives. ph adjustment medium.

Typically Found In: Virtually all cosmetic products — the most universal cosmetic ingredient globally

TECHNICAL DETAILS

Primary Category: Functional ingredient – water

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Varies widely — up to 95% in some toners and serums

SOURCING & ETHICS

Vegan Status: Yes – water (deionised/purified)

Halal Status: Yes

Source Notes: Cosmetic-grade water is purified (deionised, distilled, or ro filtered) to prevent mineral content interference with formulation stability. european pharmacopoeial water (aqua purificata ph. eur.) is the quality standard for pharmaceutical and high-end cosmetic formulations.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – non-irritant

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Water's position as the first inci ingredient on most cosmetic labels reflects the regulatory requirement to list ingredients in descending concentration order — meaning water is the most abundant ingredient in the majority of cosmetic products. the fundamental role of water as the universal cosmetic solvent and vehicle makes it simultaneously the most important cosmetic ingredient and the one that requires the most sophisticated formulation chemistry to control — every emulsifier, thickener, preservative, and ph adjuster exists primarily to manage water's interaction with other ingredients in formulation.

Last Verified: Cosing database,eu cosmetics regulation 1223/2009 inci requirements,ph. eur. aqua purificata monograph

Primary Sources: 2026-03-12