
Highlights
WHAT IS IT?
Dual-phase firming serum
FEATURES
Dual-chamber formula, sapphire-bound biomimetic peptides, plant-derived bio-extracts, next-generation Hyaluronic Acid
BEST FOR
normal
CHECKS
Paraben-free, artificial colors-free, fragrances-free, gluten-free
Who Is It For?
Mature SkinWhat Does It Help With?
Fine Lines Wrinkles Loss Of Firmness And ElasticityBudget
Professional (over $150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What dermalogica Says
Product Description:
Reawakening dual-phase serum firms and lifts skin to reduce visible signs of skin aging and help defend against the appearance of future damage. Features dual-chamber formula with sapphire-bound biomimetic peptides and plant-derived bio-extracts.
About the Brand:
Ingredients Overview
Ingredients List
Water/Aqua/Eau, 1,2-Hexanediol, Adipic Acid/Neopentyl Glycol Crosspolymer, Glycerin, Chondrus Crispus Extract, PEG-40 Hydrogenated Castor Oil, Palmitoyl Tripeptide-28, Hydroxyacetophenone, Caffeyl Glucoside, Sodium Hyaluronate, Lavandula Hybrida Oil, Eucalyptol, Lavandula Angustifolia (Lavender) Flower Extract, Plantago Lanceolata Extract, Tamarindus Indica Seed Gum, Acer Rubrum Extract, Curcuma Longa (Turmeric) Root Extract, Cistus Monspeliensis Flower/Leaf/Stem Extract, Myrciaria Dubia Fruit Extract, Glyceryl Caprylate, Maltodextrin, Pentylene Glycol, Sodium Acetylated Hyaluronate, Succinoglycan, Glucose, Xanthan Gum, Sodium Hydroxide, Glutathione, Synthetic Sapphire, Citric Acid, Propanediol, Benzoic Acid, Linalool, Benzyl Alcohol, Limonene. Isoamyl Laurate, Octyldodecanol, Isohexadecane, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Silica Silylate, Pentaclethra Macroloba Seed Oil, Pseudozyma Epicola/Camellia Sinensis Seed Oil Ferment Extract Filtrate, Spilanthes Acmella Flower Extract, Astragalus Membranaceus Root Extract, Curcuma Longa (Turmeric) Root Extract, Melia Azadirachta Leaf, Eclipta Prostrata Extract, Eclipta Prostrata Leaf Extract, Corallina Officinalis Extract, Melia Azadirachta Bark Extract, Moringa Oleifera Seed Oil, Ocimum Basilicum (Basil) Flower/Leaf Extract, Ocimum Sanctum Leaf Extract, Ethylcellulose, Carthamus Tinctorius (Safflower) Seed Oil, Hydroxyacetophenone, Caprylic/Capric Triglyceride, Lavandula Hybrida Oil, Lavandula Spica (Lavender) Flower Oil, Melia Azadirachta Flower Extract, Eucalyptus Globulus Leaf Oil, PEG-40 Hydrogenated Castor Oil, Hydroxymethoxyphenyl Decanone, Ubiquinone, Water/Aqua/Eau, Linalool, Limonene, Tocopherol, Geraniol.
Key Ingredients
Sapphire-bound biomimetic peptides, Hyaluronic Acid, Moroccan Rockrose Extract, Madagascar Green Coffee Bean, Amazonian Camu Camu
Ingredients Details
12 Hexanediol
Common Name(s): 12 hexanediol
DESCRIPTION
What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.
Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.
How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ enzymes, receptors, structural proteins, or signaling molecules โ triggering beneficial biological responses.
Typically Found In: Serums,treatments,moisturizers,specialty products
TECHNICAL DETAILS
Primary Category: Specialty actives
Secondary Functions: Skin-conditioning,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Specialty active ingredient; check individual sourcing for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1899-12-31 00:00:00 -0800
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides
Avoid Combining With: Incompatible with oxidizing agents; check ph stability
SCIENTIFIC NOTE
Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Adipic Acid/neopentyl Glycol Crosspolymer
Common Name(s): Adipic acid/neopentyl glycol crosspolymer
DESCRIPTION
What It Does: Loosens corneocyte adhesion in the stratum corneum, accelerating cell turnover, refining skin texture, and improving radiance.
Why It's Used: Organic acids at cosmetic ph values provide controlled keratolytic exfoliation that improves skin texture, pore appearance, and radiance without mechanical irritation.
How It Works: At appropriate ph, the acid's undissociated form penetrates the stratum corneum and dissolves the ionic bonds between corneocyte desmosomes (calcium chelation mechanism), facilitating controlled desquamation and cell renewal.
Typically Found In: Toners,exfoliants,serums,peels,cleansers
TECHNICAL DETAILS
Primary Category: Exfoliants
Secondary Functions: Brightening,keratolytic
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5โ20%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or plant-derived acid; no animal components.
SKIN COMPATIBILITY
Irritancy Rating: 2
Comedogenicity Rating: 0
Sensitivity Concerns: May cause irritation or stinging in sensitive or barrier-compromised skin at high concentrations; patch test recommended.
Safe for Sensitive Skin: Conditional
SAFETY & COMPATIBILITY
Safety Profile: Safe within recommended ph and concentration ranges. sensitization risk increases above 10% aha. patch test recommended for sensitive skin. mildly irritating to some individuals at typical cosmetic use concentrations.
Works Well With: Niacinamide,hyaluronic acid,ceramides,vitamin c
Avoid Combining With: High concentrations on sensitive/broken skin; avoid with physical exfoliants
SCIENTIFIC NOTE
Cosmetic acids function at the pka boundary: only the undissociated acid (rcooh) penetrates the stratum corneum lipid barrier, while the ionized carboxylate (rcooโป) does not. the henderson-hasselbalch equation governs the fraction of active species at formulation ph; typically 0.5โ3.0% undissociated acid provides efficacy while minimizing irritation.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Caffeyl Glucoside
Common Name(s): Caffeyl glucoside
DESCRIPTION
What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.
Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.
How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ enzymes, receptors, structural proteins, or signaling molecules โ triggering beneficial biological responses.
Typically Found In: Serums,treatments,moisturizers,specialty products
TECHNICAL DETAILS
Primary Category: Specialty actives
Secondary Functions: Skin-conditioning,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Specialty active ingredient; check individual sourcing for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1
Comedogenicity Rating: 0
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides
Avoid Combining With: Incompatible with oxidizing agents; check ph stability
SCIENTIFIC NOTE
Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Chondrus Crispus Extract
Common Name(s): Chondrus crispus extract
DESCRIPTION
What It Does: Provides antioxidant protection, soothing anti-inflammatory effects, and skin-conditioning benefits through plant-derived polyphenols and phytochemicals.
Why It's Used: Plant extracts concentrate bioactive phytochemicals evolved for environmental protection โ uv, microbial, and oxidative stressors โ that translate to skin benefits.
How It Works: Polyphenols (flavonoids, phenolic acids) inhibit nf-ฮบb-mediated inflammatory signaling, scavenge reactive oxygen species through electron donation, and chelate pro-oxidant metal ions to reduce oxidative skin damage.
Typically Found In: Serums,toners,moisturizers,masks,essences
TECHNICAL DETAILS
Primary Category: Botanical extracts
Secondary Functions: Antioxidant,anti-inflammatory
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1โ10%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract; no animal components.
SKIN COMPATIBILITY
Irritancy Rating: 1
Comedogenicity Rating: 0
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,ceramides
Avoid Combining With: Strong oxidizing agents
SCIENTIFIC NOTE
Plant secondary metabolites (flavonoids, terpenes, phenolic acids) are biosynthesized as defense compounds against uv, herbivores, and pathogens. their anti-inflammatory activity typically derives from competitive inhibition of cox-2 and 5-lox enzymes (ic50 1โ50 ยตm), while antioxidant activity involves single electron transfer (set) and hydrogen atom transfer (hat) mechanisms with structure-dependent rate constants.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; phytochemical and ethnobotanical literature
Primary Sources: 2025-01-15