Nioxin
Nioxin Scalp + Hair Thickening System 3 Leave-On Treatment
Nioxin Pro Clinical's System Kit 3 is designed for dry, damaged, colored hair with light thinning. Clinically and dermatologically tested, the hair thickening treatment nourishes and strengthens each strand of hair from root to tip, resulting in thicker, fuller hair.
Color-safe
Thinning
Breakage
Fine
Color-treated
Chemically Treated
Optimized for Your Environment & Lifestyle
Nykaa
In stock
Recommended
Nioxin Scalp + Hair Thickening System 3 Leave-On Treatment
Nioxin
nioxin-scalp-hair-thickening-system-3-leave-on-treatment
Leave-On Treatment
10365019324709
Morning or Evening?
How often will you use this product?
Notes
Secure payment protection
Your Biodata Compatibility Analysis
Based on your 6 hair health indices and environmental factors
Poor Match
Significant incompatibilities
Growth Cycle Health Index
Hair Match
Hair Health Index Alignment
Optimal for OSI, SSI, DI, HSI
Ingredient Efficacy
Matching Ingredient Score
Environment Compatibility
Current UV, Air Quality & Humidity
Why This Works for Your Specific Profile
Damage Index:
Damage levels outside specified range may not benefit optimally from product formulation
Water Quality:
Sensitive scalps experience irritation from active ingredients formulated for resilient skin
Hair:
No porosity-specific conflicts
Active Lifestyle:
Activity levels outside optimal range affect product performance and maintenance requirements
Your Hair Profile Integration
Your Hair Archetype
Density Level
Washing Frequency
Shedding Level
Oil Level
Your Hair Health Indices
Oil Secretion (OSI)
Very low oil production
Scalp Sensitivity (SSI)
Very low sensitivity
Growth Rate (CMR)
Poor metabolism rate
Damage Index (DI)
Minimal damage
Hair Strength (HSI)
Very weak strength
Softness Index (SI)
Significant improvement needed
Water & Environmental Integration
Water:
Expected Results & Timeline
Key Highlights
What is it?
Leave-On Treatment with 30 ingredients
Who Is It For
Adults
Budget
$42.00 - $84.00
Timeline
Visible results in just 30 days
Why Youโll Love It
What Does It Help With?
Thinning, Breakage
Best for
Thinning
Features
Thickens the hair, Nourishes the scalp
Checks
Ingredients Overview
Ingredients List
aqua-water-eau, niacinamide, caffeine, phenoxyethanol, sodium-benzoate, benzyl-alcohol, acrylates-c10-30-alkyl-acrylate-crosspolymer, polysorbate-80, polysorbate-60, acetamide-mea, triethanolamine, peg-23m, tetrasodium-edta, propylene-glycol, methyl-nicotinate, parfum-fragrance, mentha-arvensis-leaf-oil, mentha-piperita-peppermint-oil, peg-30-dipolyhydroxystearate, trideceth-6, limonene, camellia-sinensis-leaf-extract, silica, cystine-bis-pg-propyl-silanetriol, biotin, tocopheryl-acetate, lecithin, foeniculum-vulgare-fennel-fruit-extract, acer-saccharum-sugar-maple-extract, citrus-limon-lemon-peel-extract, saccharum-officinarum-sugar-cane-extract-extrait-de-canne-a-sucre, vaccinium-myrtillus-leaf-extract, faex-extract-yeast-extract-extrait-de-levure, propylparaben, citrus-aurantium-dulcis-orange-fruit-extract, bht, maltodextrin, methylparaben, potassium-sorbate, ethylparaben, butylparaben
Key Ingredients
niacinamide, caffeine, mentha-arvensis-leaf-oil, mentha-piperita-peppermint-oil, camellia-sinensis-leaf-extract, biotin, tocopheryl-acetate
Ingredients Details
Bht
Common Name(s): Bht
DESCRIPTION
What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.
Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.
How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix โ enzymes, receptors, structural proteins, or signaling molecules โ triggering beneficial biological responses.
Typically Found In: Serums,treatments,moisturizers,specialty products
TECHNICAL DETAILS
Primary Category: Specialty actives
Secondary Functions: Skin-conditioning,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01โ5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Specialty active ingredient; check individual sourcing for vegan status.
SKIN COMPATIBILITY
Irritancy Rating: 1
Comedogenicity Rating: 0
Sensitivity Concerns: Low sensitization potential at recommended use concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides
Avoid Combining With: Incompatible with oxidizing agents; check ph stability
SCIENTIFIC NOTE
Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-ฮณ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Biotin
Common Name(s): Vitamin b7,vitamin h,d-biotin
CAS Number: 58-85-5
DESCRIPTION
What It Does: Supports keratin production for stronger hair and nails.
Why It's Used: Hair and nail keratin infrastructure support; widely marketed despite evidence being primarily oral supplementation-based.
How It Works: Coenzyme for carboxylase enzymes essential for fatty acid synthesis and amino acid metabolism relevant to hair follicle function.
Typically Found In: Hair growth shampoos,nail treatments,multivitamin products
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin b7
Secondary Functions: Hair growth support,nail strengthening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Evidence for topical biotin efficacy in hair growth is limited โ most clinical evidence comes from oral supplementation in biotin-deficient individuals.
Last Verified: Cosing database,cir safety assessment,patel et al. (2017) skin appendage disorders
Primary Sources: 2026-03-12
Biotin
Common Name(s): Vitamin b7,vitamin h,d-biotin
CAS Number: 58-85-5
DESCRIPTION
What It Does: Supports keratin production for stronger hair and nails.
Why It's Used: Hair and nail keratin infrastructure support; widely marketed despite evidence being primarily oral supplementation-based.
How It Works: Coenzyme for carboxylase enzymes essential for fatty acid synthesis and amino acid metabolism relevant to hair follicle function.
Typically Found In: Hair growth shampoos,nail treatments,multivitamin products
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin b7
Secondary Functions: Hair growth support,nail strengthening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.01%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Evidence for topical biotin efficacy in hair growth is limited โ most clinical evidence comes from oral supplementation in biotin-deficient individuals.
Last Verified: Cosing database,cir safety assessment,patel et al. (2017) skin appendage disorders
Primary Sources: 2026-03-12
Butylparaben
Common Name(s): Cosmetic preservative,microbial growth inhibitor,product stability agent
CAS Number: N/a
DESCRIPTION
What It Does: Prevents microbial contamination that would otherwise render water-containing cosmetics unsafe โ inhibiting bacterial, fungal, and yeast growth through membrane disruption, enzyme inhibition, or metabolic interference at permitted regulatory concentrations.
Why It's Used: Preservatives are safety-critical โ un-preserved water-containing cosmetics can develop dangerous microbial contamination (pseudomonas aeruginosa eye infections, s. aureus skin infections) within days. preservation is a regulatory requirement, not an optional enhancement.
How It Works: Mechanism varies by class: organic acids (benzoic, dehydroacetic) disrupt intracellular ph in bacteria and fungi by proton flux across membranes; parabens inhibit membrane-associated enzyme function; chlorhexidine disrupts bacterial and fungal membrane integrity through divalent ion chelation of membrane phospholipids.
Typically Found In: All aqueous formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: Check annex v eu limits
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Eu regulation 1223/2009 annex v lists all permitted preservatives with maximum concentrations โ preservatives not listed are prohibited. formulators must verify both permitted status and maximum concentration for each market before finalising preservation systems.
Last Verified: Eu regulation 1223/2009 annex v,cosmetic preservative regulatory review
Primary Sources: 2026-03-12
Personalized Usage Instructions
How to Use
Step 1
Apply the Scalp + Hair Thickening Treatment directly to the scalp
Step 2
Shake it well before applying directly to the entire scalp
Step 3
Gently massage it in
Step 4
Do not rinse
Medical Chemicals
Protein/Moisture
- Protein/Moisture balance
pH Level
- Acidic
Porosity Taget
- High Porosity
Customized for Your Profile
Scalp Condtions
Sensitive Scalp, pH Balanced
Climate Suitability
Humid, Dry, UV Protection
Clinical Claims
85% of consumers noticed a thickening effect, 80% noticed an increase in hair density, 80% noticed an increase in hair fullness
Frequency
Apply the Scalp + Hair Thickening Treatment directly to the scalp. Shake it well before applying directly to the entire scalp. Gently massage it in. Do not rinse.