
Highlights
WHAT IS IT?
Serum with 10% Niacinamide and zinc
FEATURES
Nourishes and brightens skin, reduces blemishes and congestion, minimizes acne breakouts, improves pigmentation, reduces sun damage and dark spots, moisturizes and soothes with antioxidant and anti-inflammatory properties, supports microbiome balance
BEST FOR
sensitive
CHECKS
Sulfates, dyes, parabens, mineral oils, alcohols, fragrances, silicones
Who Is It For?
What Does It Help With?
Brightening Pigmentation Improvement Acne Control Moisture Balance Skin SoothingBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Nature Derma Says
Product Description:
This serum contains 10% Niacinamide, Zinc, Natural Biome Boost solution and Avocado extract, which nourish and brighten the skin, reduce blemishes and signs of congestion, and minimize acne breakouts. The serum also includes a unique Natural Biome-Boost Solution, which helps maintain a healthy balance in your skin's microbiome, a barrier between your skin and environmental stressors like pathogens, toxins, pollution, and sun damage. This delicate barrier is strengthened with each use of the serum, resulting in improved moisture levels and healthy, balanced skin. The Niacinamide in the serum helps improve pigmentation and helps reduce sun damage and dark spots. Zinc is an effective ingredient in helping control acne breakouts and blackheads. Avocado extract is known to moisturize, relieve, and soothe skin conditions with its antioxidant and anti-inflammatory properties. The Natural Biome-Boost Solution works to preserve a healthy microbiome balance on the skin's surface, aids in reduction of damage from environmental triggers and promoting healthy skin. Nature Derma is an innovative combination of potent actives and Natural Biome Boost solution, that helps deliver visible Results with Responsibility. These products are Dermatologically Tested and are free from sulfates, dyes, parabens, mineral oils, alcohols, fragrances, and silicones.
About the Brand:
Ingredients Overview
Ingredients List
Purified-Water,Niacinamide,Propylene-Glycol,Sodium-PCA,Zinc-PCA,Phenoxyethanol-and-Ethylhexylglycerin,Sodium-Benzoate,Aloe-Barbadensis-Extract,Citric-Acid,Hydroxyethylcellulose,Sodium-Gluconate,Xanthan-Gum,Arctium-Lappa-Root-Extract,Persea-Gratissima-Oil
Key Ingredients
Niacinamide,Zinc,Avocado Extract,Natural Biome-Boost Solution
Ingredients Details
Hydroxyethylcellulose
Common Name(s): Hec,natrosol,ethylhydroxyethylcellulose
CAS Number: 9004-62-0
DESCRIPTION
What It Does: Provides non-ionic thickening compatible with anionic surfactants and electrolyte-containing formulations.
Why It's Used: Non-ionic cellulose thickener for surfactant systems where anionic/cationic thickener incompatibility is a concern.
How It Works: Hydroxyethyl substitution disrupts cellulose crystallinity enabling water solubility. non-ionic nature provides compatibility with anionic, cationic, and amphoteric surfactants. pseudoplastic rheology provides shear-thinning for dispensing. film formation from cellulose backbone.
Typically Found In: Shampoos,body washes,clear gels,surfactant systems
TECHNICAL DETAILS
Primary Category: Functional ingredient โ cellulose thickener
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Yes โ from cellulose (plant)
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Hydroxyethylcellulose's non-ionic character is its primary differentiator from anionic carboxymethylcellulose โ the absence of ionizable groups means hec maintains stable viscosity across ph 2-12 and at high electrolyte concentrations where carboxymethylcellulose destabilizes. this ionic independence makes hec the preferred cellulose thickener for acidic and salt-containing formulations.
Last Verified: Cosing database,ashland hec technical data,cir safety assessment
Primary Sources: 2026-03-12
Niacinamide
Common Name(s): Vitamin b3,nicotinamide,pyridine-3-carboxamide
CAS Number: 98-92-0
DESCRIPTION
What It Does: Niacinamide strengthens the skin barrier, reduces visible pore size, regulates sebum production, fades dark spots, and improves skin texture and tone.
Why It's Used: It is used because it addresses multiple skin concerns at once without irritation, making it suitable for all skin types. it is stable in formulations and pairs well with most other actives.
How It Works: Niacinamide inhibits the transfer of melanosomes (pigment packets) to skin cells, reducing hyperpigmentation. it also stimulates ceramide synthesis to strengthen the skin barrier and reduces inflammation by modulating cytokine activity.
Typically Found In: Serums,moisturizers,toners,cleansers,eye creams,sunscreens,primers
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin
Secondary Functions: Barrier repair,brightening,anti-inflammatory
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 2%โ10% (typical: 5%; higher concentrations may cause flushing in some individuals)
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes โ synthetic origin
Source Notes: Commercially produced via synthesis from nicotinic acid or 3-cyanopyridine. no animal-derived sources used in cosmetic-grade niacinamide.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; concentrations above 10% may cause temporary flushing in sensitive individuals
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: At concentrations >10%, some users experience niacin flush (transient redness/tingling). generally very well-tolerated.
Safe for Sensitive Skin: Yes โ one of the best-tolerated actives for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Extensively studied and considered very safe. ewg hazard score: 1. no significant systemic toxicity concerns at topical concentrations.
Works Well With: Retinol,peptides,ahas/bhas,hyaluronic acid,ceramides,zinc,vitamin c,spf
Avoid Combining With: High concentrations of vitamin c (ascorbic acid) may theoretically convert to niacin โ use at different times if using pure l-ascorbic acid above 15%
SCIENTIFIC NOTE
Niacinamide is a precursor to nad+ and nadp+, coenzymes vital to cellular energy metabolism. its benefits for dna repair and mitochondrial function make it a key ingredient in anti-aging strategies.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,pubmed clinical studies
Primary Sources: 2026-03-12