
Highlights
WHAT IS IT?
Soothing essence drenched sheet mask, 5 ingredients
FEATURES
Close fit skinny sheet contours to face, silky soft non irritating fabric softer than cotton sheets, helps control bacterial growth, soothes and rejuvenates skin, restores balance to sensitive skin
BEST FOR
sensitive
CHECKS
No preservatives explicitly mentioned, no fragrance mentioned
Who Is It For?
What Does It Help With?
Soothes Irritated Skin Restores Skin BalanceBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What MEDIHEAL Says
Product Description:
Mediheal Pure Calming Mask Anti Aging Care ] 20ml Essence drenched soothing mask helps to restore balance to sensitive skin 1. Main ingredients of the mask help to soothe and rejuvenate the skin 2 . Soothes irritated skin 3 . Mask drenched in soothing essence
About the Brand:
Ingredients Overview
Ingredients List
Adenosine,Cynanchum-Atratum-Extract,Artemisia-Princeps-Leaf-Extract,Centella-Asiatica-Extract,Allantoin
Key Ingredients
Adenosine,Cynanchum Atratum Extract,Artemisia Princeps Leaf Extract,Centella Asiatica Extract,Allantoin
Ingredients Details
Adenosine
Common Name(s): Adenine riboside,9-beta-d-ribofuranosyladenine
CAS Number: 58-61-7
DESCRIPTION
What It Does: Reduces fine lines, stimulates collagen, firms skin, and reduces inflammation.
Why It's Used: Fda-recognized anti-wrinkle active with multi-action collagen stimulation + wrinkle reduction + anti-inflammatory efficacy.
How It Works: Activates adenosine a2a receptors on fibroblasts stimulating collagen type i. also activates pka pathway promoting atp production and reducing inflammatory cytokines.
Typically Found In: Anti-aging serums,wrinkle treatments,korean skincare
TECHNICAL DETAILS
Primary Category: Active ingredient โ purine nucleoside / anti-aging
Secondary Functions: Collagen stimulation,anti-inflammatory,cell energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.04%โ0.1%
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes
Source Notes: Synthetically produced for cosmetic use.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; excellent tolerability.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. fda-recognized as safe and effective anti-wrinkle ingredient. ewg score: 1.
Works Well With: Other b vitamins,niacinamide,antioxidant complexes
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
A 2002 clinical study demonstrated 0.04% adenosine cream significantly reduced wrinkle depth and increased skin elasticity after 4 weeks. fda recognition requires controlled clinical trial evidence.
Last Verified: Cosing database,adenosine anti-aging clinical data,fda otc anti-wrinkle monograph
Primary Sources: 2026-03-12
Allantoin
Common Name(s): 5-ureidohydantoin,glyoxyldiureide,aluminum dihydroxy allantoinate
CAS Number: 97-59-6
DESCRIPTION
What It Does: Soothes irritation, accelerates wound healing, promotes skin cell renewal, and provides mild keratolytic exfoliation.
Why It's Used: Gold standard multi-function soothing active โ one of the most widely used cosmetic ingredients across all product types for its exceptional tolerability and clinically proven multi-action skin conditioning.
How It Works: Promotes keratinocyte proliferation and fibroblast migration for wound healing. mild keratolytic activity by disrupting corneocyte binding. anti-irritant via direct protein binding and anti-inflammatory cytokine reduction. humectant activity via hydroxyl groups.
Typically Found In: Post-procedure products,sensitive skin formulas,wound care,anti-acne treatments,baby products
TECHNICAL DETAILS
Primary Category: Active ingredient โ soothing / anti-inflammatory
Secondary Functions: Wound healing,keratolytic,anti-irritant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic or comfrey-derived
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Exceptionally well-tolerated; suitable for all skin types including baby and compromised skin.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Allantoin's keratinocyte proliferation stimulation occurs via receptor-mediated signaling (possibly machr activation) rather than non-specific irritation-driven proliferation, making it a true wound-healing stimulant rather than a pro-inflammatory proliferative signal.
Last Verified: Cosing database,cir safety assessment,araรบjo et al. allantoin review
Primary Sources: 2026-03-12