Mediheal Derma Synergy Mask Retinol X Lha 4S

MEDIHEAL

Mediheal Derma Synergy Mask Retinol X Lha 4S

Mediheal Derma Synergy Mask Retinol X Lha 4S

MEDIHEAL

mediheal-derma-synergy-mask-retinol-x-lha-4s

Face Mask

10085015322917

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

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Compatibility Score

0%

Microbiome
Ingredients
Biological
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How It Fits Into Your Skincare Routine

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Highlights

WHAT IS IT?

Face Mask with multiple active ingredients

FEATURES

Synergic effect of retinol and LHA, pore tightening, improves skin elasticity, clear pores, firm elasticity, reduces pore size and depth

BEST FOR

sensitive

CHECKS

Sodium Lauryl Sulfate

Who Is It For?

What Does It Help With?

Pore Shrinking Skin Elasticity Firming Pore Tightening Clear Pores

Budget

Mid-range ($30-$75)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

1. After washing your face, prepare your skin with lotion. Take out the mask sheet and attach it to the shape of your face.
2. Remove the mask in 10-20 minutes and lightly pat the remaining essence to absorb into the skin.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What MEDIHEAL Says

Product Description:

[RetinolXLHA Derma Synergy Mask]
The synergic effect between two different ingredients provide pore and skin elasticity care.
100% satisfaction in intensive pore astriction, pore tightening, clear pores, and firm elasticity.
Pore size reduced by 38.3%, pore depth improved by 14.4%, pore tightening by 4.8%, and skin elasticity improved by 6.83% after single use.
Tightens stretched and wide pores and provides suppleness to exhausted skin.

About the Brand:

Mediheal revolutionized the sheet mask category with its professional-grade treatments and innovative delivery systems. Offering targeted solutions for every skin concern, this Korean brand brings clinical effectiveness to at-home skincare. Experience the transformative power of advanced sheet mask technology with Mediheal's professional treatments.

Ingredients Overview

Ingredients List

Extract,Squalane,Caprylic/Capric-Triglyceride,Rosa-Damascena-Flower-Water,Panthenol,Lecithin,Macadamia-Ternifolia-Seed-Oil,Sodium-Lauryl-Sulfate,Tremella-Fuciformis-Polysaccharide,Linum-Usitatissimum-(Linseed)-Seed-Extract,Bambusa-Vulgaris-Leaf-Extract,Pantothenic-Acid,Sodium-Ascorbyl-Phosphate,Mangifera-Indica-(Mango)-Fruit-Extract,Olea-Europaea-(Olive)-Oil-Unsaponifiables,Ceramide-NP,Glycine-Soja-(Soybean)-Oil-Unsaponifiables,Triticum-Vulgare-(Wheat)-Germ-Oil-Unsaponifiables,Cholesterol,Stearic-Acid,Pollen-Extract,Hydroxypropyltrimonium-Hyaluronate,Sodium-Acetylated-Hyaluronate,Hydrolyzed-Hyaluronic-Acid,Hyaluronic-Acid,Sodium-Hyaluronate-Crosspolymer,Hydrolyzed-Sodium-Hyaluronate,Potassium-Hyaluronate

Key Ingredients

Retinol,LHA,Panthenol,Squalane,Ceramide NP

Ingredients Details

Cholesterol

Common Name(s): 5-cholesten-3-ol,cholesterin

CAS Number: 57-88-5

DESCRIPTION

What It Does: Provides essential barrier sterol function as one of three critical stratum corneum lipid components.

Why It's Used: Essential component of complete barrier repair formulations โ€“ the stratum corneum barrier requires ceramides:cholesterol:fatty acids in approximately 1:1:1 molar ratio for complete barrier restoration.

How It Works: Integrates between ceramide headgroups in lamellar body structures, providing fluidity and flexibility to the otherwise rigid ceramide-dominated lipid matrix. controls lamellar body phase behavior for functional barrier.

Typically Found In: Barrier repair moisturizers,eczema treatments,dry skin formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ barrier sterol

Secondary Functions: Lamellar body structure,barrier sterol

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%โ€“1%

SOURCING & ETHICS

Vegan Status: Conditional โ€“ animal-derived (lanolin) or plant-derived phytosterol analogs; verify

Halal Status: Conditional โ€“ verify source

Source Notes: Traditionally from lanolin (wool grease). plant-derived cholesterol alternatives include phytosterols, though these show slightly different barrier integration. verify for vegan/halal.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Endogenous molecule; excellent tolerability.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. natural skin component. ewg score: 1.

Works Well With: Other ceramides,cholesterol,free fatty acids,hyaluronic acid,niacinamide

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Elias demonstrated that barrier repair requires all three lipid classes (ceramides, cholesterol, fatty acids) in approximately equimolar ratios. formulations providing only ceramides without cholesterol and fatty acids show significantly inferior barrier restoration vs complete triple-lipid combinations.

Last Verified: Cosing database,elias et al. barrier lipid ratio study,loden barrier repair review

Primary Sources: 2026-03-12

Lecithin

Common Name(s): Soy lecithin,sunflower lecithin,phosphatidylcholine complex

CAS Number: 8002-43-5

DESCRIPTION

What It Does: Provides natural phospholipid emulsification with barrier-compatible delivery and liposome-forming properties.

Why It's Used: The most biologically authentic emulsifier โ€“ identical to cell membrane composition providing barrier-compatible delivery and liposome formation unavailable from synthetic emulsifiers.

How It Works: Phosphatidylcholine (pc), phosphatidylethanolamine (pe), phosphatidylinositol (pi) mixture provides hlb 7-12 for o/w emulsification. forms liposomal bilayers for active encapsulation. pc/pe/pi composition mirrors cell membrane for barrier-compatible delivery.

Typically Found In: Natural cosmetics,liposomal products,barrier repair,penetration-enhanced formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ natural phospholipid emulsifier

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional โ€“ soy lecithin (vegan); egg lecithin (not vegan)

Halal Status: Conditional โ€“ soy (halal); egg (verify)

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Lecithin's phospholipid composition mirrors the composition of the stratum corneum's own lamellar bodies that deliver barrier lipids to the skin surface. this structural mimicry allows lecithin-based delivery systems to integrate seamlessly with the barrier lipid structure, exploiting the same transport pathway the skin uses for its own lipid secretion.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

Panthenol

Common Name(s): Provitamin b5,d-panthenol,dl-panthenol,d-pantothenyl alcohol,(r)-2,4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethylbutanamide

DESCRIPTION

What It Does: Panthenol deeply moisturizes skin and hair, soothes irritation, accelerates wound healing, strengthens the skin barrier, and improves hair elasticity and shine.

Why It's Used: It is used because it is exceptionally versatile, working in both skin and hair formulations. it is gentle enough for sensitive and post-procedure skin, and converts to the active vitamin b5 within the skin.

How It Works: Panthenol penetrates skin and hair, where it is oxidized to pantothenic acid (vitamin b5), a coenzyme a precursor essential to metabolism. in skin, it acts as a humectant and stimulates fibroblast proliferation. in hair, it coats the shaft, improving manageability.

Typically Found In: Moisturizers,serums,toners,after-sun products,wound healing products,shampoos,conditioners,hair masks,beard care

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ provitamin b5

Secondary Functions: Anti-inflammatory,wound healing,hair conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%โ€“5% (typical: 1โ€“3%)

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetically produced

Halal Status: Yes

Source Notes: Commercially synthesized. both d- and dl-forms used in cosmetics; d-panthenol is the biologically active isomer but dl-panthenol is less expensive and widely used.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low; one of the most soothing ingredients in cosmetics

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Extremely rare contact allergy; considered one of the safest cosmetic ingredients. suitable for all skin types.

Safe for Sensitive Skin: Yes โ€“ ideal for sensitive, reactive, and post-procedure skin

SAFETY & COMPATIBILITY

Safety Profile: Exceptionally safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or systemic toxicity. safe during pregnancy.

Works Well With: Hyaluronic acid,ceramides,allantoin,niacinamide,centella asiatica,retinol (reduces irritation),glycerin

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Panthenol has demonstrated wound-healing properties in clinical studies, stimulating fibroblast proliferation and migration. its dual humectant and anti-inflammatory action makes it particularly effective in barrier-repair formulations.

Last Verified: Cosing database,cir safety assessment,ebner et al. (2002) skin pharmacology and applied skin physiology

Primary Sources: 2026-03-12

Squalane

Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane

CAS Number: 0111-01-03

DESCRIPTION

What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.

Why It's Used: The most skin-compatible emollient โ€“ chemically identical to human sebum squalene component with outstanding tolerability across all skin types.

How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.

Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ emollient

Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“100%

SOURCING & ETHICS

Vegan Status: Conditional โ€“ plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out

Halal Status: Yes โ€“ plant-derived

Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Squalene constitutes approximately 12-15% of human sebum โ€“ the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.

Last Verified: Cosing database,huang et al. squalane review,cir safety assessment

Primary Sources: 2026-03-12