
Highlights
WHAT IS IT?
Scar treatment gel with 2 active ingredients
FEATURES
Combination of Allium cepa extracts and Allantoin, patented scar treatment, greasy free, dermatologist and consumer trusted, reduces scars from cut marks, burns, injury, surgery, acne and C-section surgery
BEST FOR
sensitive
CHECKS
Do not contain deep wounds cautions, no preservatives mentioned explicitly
Who Is It For?
All Genders No Age Restriction StatedWhat Does It Help With?
Visibly Reducing Appearance Of ScarsBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Mederma Says
Product Description:
Mederma Gel formulation is a combination of Allium cepa extracts and Allantoin. Mederma skin care for scars is a patented scar treatment gel with cepalin that helps scars appear softer and smoother. It is a greaseless gel, easy and convenient to use. It helps in visibly reducing the appearance of scars caused from Cut marks, Burns, Injury, Surgery, Acne and C-section surgery. Mederma Gel is USA's No.-1 Pharmacist recommended brand in scar category for past 15 years in a row.
About the Brand:
Ingredients Overview
Ingredients List
Cepalin, Allantoin
Key Ingredients
Cepalin,Allantoin
Ingredients Details
Allantoin
Common Name(s): 5-ureidohydantoin,glyoxyldiureide,aluminum dihydroxy allantoinate
CAS Number: 97-59-6
DESCRIPTION
What It Does: Soothes irritation, accelerates wound healing, promotes skin cell renewal, and provides mild keratolytic exfoliation.
Why It's Used: Gold standard multi-function soothing active โ one of the most widely used cosmetic ingredients across all product types for its exceptional tolerability and clinically proven multi-action skin conditioning.
How It Works: Promotes keratinocyte proliferation and fibroblast migration for wound healing. mild keratolytic activity by disrupting corneocyte binding. anti-irritant via direct protein binding and anti-inflammatory cytokine reduction. humectant activity via hydroxyl groups.
Typically Found In: Post-procedure products,sensitive skin formulas,wound care,anti-acne treatments,baby products
TECHNICAL DETAILS
Primary Category: Active ingredient โ soothing / anti-inflammatory
Secondary Functions: Wound healing,keratolytic,anti-irritant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic or comfrey-derived
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Exceptionally well-tolerated; suitable for all skin types including baby and compromised skin.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Allantoin's keratinocyte proliferation stimulation occurs via receptor-mediated signaling (possibly machr activation) rather than non-specific irritation-driven proliferation, making it a true wound-healing stimulant rather than a pro-inflammatory proliferative signal.
Last Verified: Cosing database,cir safety assessment,araรบjo et al. allantoin review
Primary Sources: 2026-03-12