
Highlights
WHAT IS IT?
Eye serum
FEATURES
Cooling applicator, clinically proven technology
BEST FOR
All skin types
CHECKS
Free of parabens, talc, phthalates, synthetic fragrances, fillers, GMO ingredients
Who Is It For?
Adults Both Men And WomenWhat Does It Help With?
Expression Lines Creasing Hollowness Tired EyesBudget
PremiumHow To Use
Which routine should it be used in?
Instructions:
Key Information
What ZO Skin Health Says
Product Description:
Powered by clinically proven ZO® Growth Factor technology, Growth Factor Eye Serum is designed to help improve the appearance of expression lines, creasing + hollowness while plumping + encouraging healthy skin for a visibly revived look. The cooling applicator soothes the skin + re-invigorates the look of tired eyes.
About the Brand:
Ingredients Overview
Ingredients List
Aqua/Water/Eau, Dimethicone, Dipropylene Glycol, Butylene Glycol, Glycerin, Bellis Perennis (Daisy) Flower Extract, Dimethicone/PEG-10/15 Crosspolymer, PEG/PPG-18/18 Dimethicone, Lupinus Albus Seed Oil, Triticum Vulgare (Wheat) Germ Oil, PEG-35 Castor Oil, Hieracium Pilosella Extract, Scutellaria Baicalensis Root Extract, Cordyceps Militaris Mycelium Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Angelica Polymorpha Sinesis Root Extract, Buddleja Davidii Meristem Cell Culture, Lactobacillus/Panax Ginseng Root Ferment Filtrate, Sodium Chloride, Dimethicone Crosspolymer, Lactobacillus Ferment, Phospholipids, Sodium Citrate, Sodium Tocopheryl Phosphate, Hydrolyzed Sericin, Cera Alba/Beeswax/Cire d'abeille, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Acetylated Hyaluronate, Panthenyl Triacetate, Acetyl Tyrosine, Ethyl Linoleate, 1,2-Hexanediol, Pentylene Glycol, Proline, Citric Acid, Hydrolyzed Vegetable Protein, Oleyl Alcohol, Trisodium Citrate Dihydrate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Silica, Silica Silylate, Beta-Glucan, Tocopherol, Disodium Acetyl Glucosamine Phosphate, Adenosine Triphosphate, Caprylyl Glycol, Hexylene Glycol, PEG-12 Glyceryl Laurate, Acetyl Tetrapeptide-5, Xanthan Gum, Disodium EDTA, PVP, Sodium Benzoate, Sodium Dehydroacetate, Phenoxyethanol, Potassium Sorbate.
Key Ingredients
ZO® Growth Factor Technology, Neuropeptide, Sodium acetylated hyaluronate
Ingredients Details
Butylene Glycol
Common Name(s): 1,3-butanediol,bg,1,3-butylene glycol
CAS Number: 107-88-0
DESCRIPTION
What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.
Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.
How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.
Typically Found In: Toners,essences,serums,k-beauty formulas
TECHNICAL DETAILS
Primary Category: Functional ingredient – glycol humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–10%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Dimethicone
Common Name(s): Pdms,polydimethylsiloxane,silicone fluid
CAS Number: 9006-65-9
DESCRIPTION
What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.
Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.
How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.
Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal
TECHNICAL DETAILS
Primary Category: Functional ingredient – polydimethylsiloxane
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–30%
SOURCING & ETHICS
Vegan Status: Yes – synthetic
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 1/5 – low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Dimethicone/peg-10/15 Crosspolymer
Common Name(s): Dimethicone/peg-10/15 crosspolymer
DESCRIPTION
What It Does: Reduces surface tension at oil-water interfaces, enabling effective cleansing, emulsification, and formulation stability.
Why It's Used: Surface-active agents are essential for emulsification, cleansing, and stabilization of cosmetic formulations containing both aqueous and lipid phases.
How It Works: The amphiphilic molecular structure positions the hydrophilic head in water and the lipophilic tail in oils, creating micelles that solubilize sebum, dirt, and oil-soluble impurities for rinsing in cleansers or stable emulsions in leave-on products.
Typically Found In: Cleansers,shampoos,body washes,foaming treatments
TECHNICAL DETAILS
Primary Category: Surfactants
Secondary Functions: Emulsifying,cleansing
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5–30%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or semi-synthetic surfactant; no animal components.
SKIN COMPATIBILITY
Irritancy Rating: 2
Comedogenicity Rating: 0
Sensitivity Concerns: May cause irritation or stinging in sensitive or barrier-compromised skin at high concentrations; patch test recommended.
Safe for Sensitive Skin: Conditional
SAFETY & COMPATIBILITY
Safety Profile: Well-characterized cosmetic ingredient with established safety profile. mildly irritating to some individuals at typical use concentrations. suitable for leave-on and rinse-off cosmetics.
Works Well With: Other surfactants,thickeners,conditioning agents
Avoid Combining With: High concentrations in sensitive skin formulations
SCIENTIFIC NOTE
Surfactant critical micelle concentration (cmc) determines the threshold for emulsification: above the cmc, amphiphilic molecules self-assemble into micelles with hydrophobic cores that solubilize oils. hlb (hydrophile-lipophile balance) value predicts surfactant function: hlb 3–6 for w/o emulsifiers, 8–18 for o/w emulsifiers, >15 for solubilizers.
Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature
Primary Sources: 2025-01-15
Dipropylene Glycol
Common Name(s): Dipropylene glycol,glycol co-solvent,humectant formulation aid
CAS Number: N/a
DESCRIPTION
What It Does: Provides humectant, co-solvent, and fragrance fixative in cosmetic formulations, improving active ingredient dissolution and product texture while delivering mild skin conditioning.
Why It's Used: Glycol solvents are essential for dissolving actives with limited water or oil solubility — the intermediate polarity of glycol ethers provides access to the wider solubility parameter space between pure water and oil phases.
How It Works: Hydroxyl and ether groups provide h-bonding for water miscibility; the organic chain provides compatibility with lipophilic actives. medium-chain glycols (c3–c6) provide the optimal balance of water compatibility, lipophilic active dissolution, and skin-compatible humectancy.
Typically Found In: Skin care formulations,co-solvent systems
TECHNICAL DETAILS
Primary Category: Functional ingredient – humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%–30%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Glycol ether co-solvents enhance sc penetration of co-applied actives by increasing their thermodynamic activity in the sc lipid phase — high thermodynamic activity (near saturation) drives diffusion by concentration gradient even when absolute concentration is low.
Last Verified: Cosing database,dipropylene glycol glycol solvent review
Primary Sources: 2026-03-12