Fixderma SKARFIX -TX Cream Tranexamic Acid, Alpha, Arbutin, Vitamin C & Kojic Acid 30 gm

Fixderma

Fixderma SKARFIX -TX Cream Tranexamic Acid, Alpha, Arbutin, Vitamin C & Kojic Acid 30 gm

Fixderma SKARFIX -TX Cream Tranexamic Acid, Alpha, Arbutin, Vitamin C & Kojic Acid 30 gm

Fixderma

fixderma-skarfix-tx-cream-tranexamic-acid-alpha-arbutin-vitamin-c-kojic-acid-30-gm

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Morning
Evening
Both

How often will you use this product?

Everyday
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Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

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Compatibility Score

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Highlights

WHAT IS IT?

Cream; multiple active ingredients

FEATURES

Effective for melasma and uneven skin tone, diminishes melasma PIE PIH and hyperpigmentation, contains derivative of amino acid lysine inhibiting melanin transfer, synergistic effect by alpha arbutin and vitamin E, removes dead skin cells and impurities, derivative of hydroquinone, protects skin from UV rays, anti-inflammatory, scavenges free radicals, reduces dark spots and blemishes

BEST FOR

sensitive

CHECKS

Does not contain parabens, fragrance

Who Is It For?

All Genders; No Specific Age Range Mentioned

What Does It Help With?

Melasma Hyperpigmentation Dark Spots Uneven Skin Tone Pih Inflamed Skin Free Radicals Protection

Budget

Affordable (under โ‚น30)

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Not explicitly stated in the content

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Fixderma Says

Product Description:

SkarfixTX cream is a novel approach in the treatment of melasma and uneven skin tone. A powerful cream to effectively diminish the appearance of Melasma PIE PIH and hyperpigmentation. It contains derivative of the amino acid lysine which inhibits melanin transfer with great efficacy and synergistic effect by alpha arbutin and vitamin E. It has natural demelanizing agents. It is ideal for stubborn dark spots that do not respond to other skin lightening agents. It also removes dead skin cells oil dirt and organisms that might be thriving on your skin. It reveals newer skin layer and aids in reducing the melanin production. It has choice brightening ingredient because it&aposs a derivative of hydroquinone one of the most effective skinlightening and spotfading actives out there. Vitamin E protects the skin from harmful UV rays and maintains its vitality. It also shows effects on Inflamed skin. It will help calm the skin reduce inflammation and help promote the health of the skin&aposs natural barrier. It can help scavenge and counteract skindamaging free radicals caused by exposure to things such as UV damage. It dramatically reduces dark spots and blemishes for brighter evenlooking skin. This combination of efficient actives targets the melanin from all directions to give the best possible results.

About the Brand:

Fixderma stands at the intersection of dermatological science and practical skincare solutions, addressing complex skin concerns with medical precision. Founded by dermatologists who understood the gap between clinical treatments and daily skincare, this brand has become synonymous with results-driven formulations. Their research team collaborates directly with practicing dermatologists to identify real-world skin challenges and develop targeted solutions. Each product is backed by clinical studies and formulated with pharmaceutical-grade actives at therapeutic concentrations.

Ingredients Overview

Ingredients List

tranexamic-acid,alpha-arbutin,vitamin-c,kojic-acid,lysine-derivative,vitamin-e

Key Ingredients

Tranexamic Acid, Alpha Arbutin, Vitamin C, Kojic Acid, Lysine derivative, Vitamin E

Ingredients Details

Alpha-arbutin

Common Name(s): 4-hydroxyphenyl-alpha-d-glucopyranoside

DESCRIPTION

What It Does: Provides potent tyrosinase inhibition with improved stability and tolerability over other arbutin forms.

Why It's Used: Premium arbutin โ€” alpha configuration provides 10ร— greater tyrosinase inhibition than beta-arbutin at equivalent concentration, making alpha-arbutin the most effective arbutin form.

How It Works: Alpha-glucoside linkage provides enhanced metabolic stability vs beta-arbutin (less enzymatic hydrolysis to free hydroquinone in skin). inhibits tyrosinase via competitive substrate inhibition (ic50 ~24ฮผg/ml vs beta-arbutin ~525ฮผg/ml โ€” 20ร— more potent). inhibits dopa oxidase step in melanogenesis.

Typically Found In: Brightening serums,anti-spot products,premium lightening

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ arbutin brightening agent

Secondary Functions: Melanin inhibition,hyperpigmentation reduction

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%โ€“2%

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic enzymatic synthesis

Halal Status: Yes

Source Notes: Synthetic or plant-derived.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. use with spf for maximum efficacy. ewg score: 1.

Works Well With: Niacinamide,vitamin c,alpha-arbutin,tranexamic acid,spf

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Alpha-arbutin's 10โ€“20ร— greater potency vs beta-arbutin at equivalent concentration arises from the alpha-glycosidic bond geometry โ€” the alpha configuration positions the hydroquinone aglycone at a specific orientation relative to the glucose that fits the tyrosinase active site copper more precisely than the beta isomer's different spatial arrangement.

Last Verified: Cosing database,sugimoto et al. arbutin tyrosinase study

Primary Sources: 2026-03-12