
Highlights
WHAT IS IT?
Firming and resurfacing serum
FEATURES
Rejuvenates and firms the skin from within
BEST FOR
Combination, Dry, Mature, Normal, Normal to Dry
CHECKS
Gluten-free, Oil-free
Who Is It For?
Adults (18+) Women And MenWhat Does It Help With?
Fine Lines And Wrinkles Lack Of Firmness Dark Spots Post-acne Scars Marks And ImperfectionsBudget
PremiumHow To Use
Which routine should it be used in?
Instructions:
Key Information
What Natura Bissรฉ Says
Product Description:
This night serum delivers all the power of retinol... but enhanced! We've complemented this ingredient with bakuchiol, a natural retinol-like active without potential side effects. This way, you can rejuvenate your skin every day!
About the Brand:
Ingredients Overview
Ingredients List
Water (Aqua), Propanediol, Glycolic Acid, Squalane, Dimethicone, Xylitylglucoside, Sodium Hydroxide, Polyacrylate Crosspolymer-6, Alanine, Aloe Barbadensis Leaf Juice Powder, Anhydroxylitol, Arginine, Aspartic Acid, Bakuchiol, Glycine, Histidine, Hydrolyzed Collagen, Hydrolyzed Elastin, Isoleucine, Lecithin, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, PCA, Phenylalanine, Proline, Pullulan, Retinol, Sclerotium Gum, Serine, Sodium PCA, Soluble Proteoglycan, Threonine, Valine, Xylitol, Butylene Glycol, Glucose, Glycerin, Dimethiconol, Hydroxypropyl Cyclodextrin, Carbomer, Polysorbate 20, Silica, Xanthan Gum, Disodium EDTA, Sodium Lactate, Ethylhexylglycerin, Phenoxyethanol, Tocopheryl Acetate, Fragrance (Parfum), Cinnamyl Alcohol, Citronellol, Geraniol, Hydroxycitronellal, Limonene, Linalool.
Key Ingredients
Retinol, Bakuchiol, Glycolic Acid, Aminoessence Cocktail (collagen and elastin amino acids), Matrixyl
Ingredients Details
Alanine
Common Name(s): L-alanine,2-aminopropanoic acid
CAS Number: 56-41-7
DESCRIPTION
What It Does: Provides nmf-type humectant moisture retention and skin conditioning.
Why It's Used: Simple, well-tolerated nmf amino acid humectant for skin conditioning formulations.
How It Works: Small methyl side chain contributes to protein hydrophobic core but as free amino acid provides direct humectant activity via amino and carboxyl groups. converted to pyruvate for cellular atp production via gluconeogenesis.
Typically Found In: Nmf moisturizers,skin conditioning products
TECHNICAL DETAILS
Primary Category: Active ingredient โ amino acid
Secondary Functions: Nmf component,cellular energy
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%โ5%
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived or synthetic
Halal Status: Yes
Source Notes: Fermentation-derived or synthetic. natural skin component.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; endogenous skin molecule.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. natural skin nmf component. ewg score: 1.
Works Well With: Hyaluronic acid,ceramides,peptides,other amino acids
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Free alanine is among the most abundant amino acids in the stratum corneum nmf, where it contributes to the aqueous phase hydration that keeps the stratum corneum flexible and functional.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Aloe Barbadensis Leaf Juice Powder
Common Name(s): Aloe barbadensis leaf juice powder,cosmetic active,functional ingredient
CAS Number: N/a
DESCRIPTION
What It Does: Delivers characteristic cosmetic function โ skin conditioning, protection, preservation, or active biological benefit โ at recommended use concentration.
Why It's Used: Selected for its functional contribution and formulation compatibility โ supported by cosmetic science literature and regulatory safety assessment.
How It Works: Works through the mechanism of its molecular class โ physicochemical interaction with the formulation or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed literature.
Typically Found In: Skin care formulations
TECHNICAL DETAILS
Primary Category: Active ingredient โ cosmetic active
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ10%
SOURCING & ETHICS
Vegan Status: Conditional
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Aloe barbadensis leaf juice powder delivers documented functional benefit with an established safety profile within the cosmetic regulatory framework (cosing eu, cir usa).
Last Verified: Cosing database,aloe barbadensis leaf juice powder technical literature
Primary Sources: 2026-03-12
Dimethicone
Common Name(s): Pdms,polydimethylsiloxane,silicone fluid
CAS Number: 9006-65-9
DESCRIPTION
What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.
Why It's Used: The benchmark cosmetic silicone โ sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.
How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.
Typically Found In: Moisturizers,foundations,primers,sunscreens โ nearly universal
TECHNICAL DETAILS
Primary Category: Functional ingredient โ polydimethylsiloxane
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ30%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Plant-derived, synthetic or animal-derived. verify source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 1/5 โ low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material โ explaining why even small amounts transform product feel.
Last Verified: Cosing database,cir safety assessment
Primary Sources: 2026-03-12
Glycolic Acid
Common Name(s): Hydroxyacetic acid,2-hydroxyacetic acid
CAS Number: 79-14-1
DESCRIPTION
What It Does: Provides maximum aha efficacy from the smallest most penetrating alpha-hydroxy acid.
Why It's Used: The most potent aha โ glycolic acid's smallest molecular size provides the deepest penetration and highest efficacy of any alpha-hydroxy acid for exfoliation and anti-aging.
How It Works: Smallest aha (mw 76) provides deepest stratum corneum penetration. disrupts corneodesmosomes reducing cohesion. stimulates fibroblast collagen i and iii synthesis. efficacy is ph-dependent โ free acid fraction determines activity.
Typically Found In: Chemical peels,body lotions,anti-aging serums,exfoliating toners
TECHNICAL DETAILS
Primary Category: Active ingredient โ primary aha
Secondary Functions: Brightening,collagen stimulation
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ10% cosmetic; higher professional
SOURCING & ETHICS
Vegan Status: Yes โ synthetic or fermentation-derived
Halal Status: Yes
Source Notes: Fermentation-derived or synthetic. ph must be โค4.0 for aha activity.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 โ low to moderate
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Photosensitizing โ mandatory spf use. start at low frequency.
Safe for Sensitive Skin: Use with caution โ spf required
SAFETY & COMPATIBILITY
Safety Profile: Eu cosmetics: max 10% leave-on, ph โฅ3.5, mandatory sun protection advisory. professional peel concentrations regulated separately.
Works Well With: Niacinamide,ceramides,hyaluronic acid,spf
Avoid Combining With: Retinol in same step; multiple exfoliants simultaneously
SCIENTIFIC NOTE
Glycolic acid's ph-dependent efficacy is critical: at ph 3.0 ~100% is in the free acid (membrane-permeable) form; at ph 3.5 ~70%; at ph 4.0 ~50%. the eu ph โฅ3.5 requirement reduces free acid proportion, lowering efficacy but also reducing irritation โ why professional peel concentrations at lower ph are far more active than equivalent cosmetic concentrations.
Last Verified: Cosing database,eu aha guidelines,cir safety assessment
Primary Sources: 2026-03-12