Ducray
Ducray Melascreen Anti - Spots Concentrate
Ducray Melascreen Anti - Spots Concentrate
Ducray
ducray-melascreen-anti-spots-concentrate
Serum
10085063852325
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WHAT IS IT?
Anti-spot concentrate with 15% depigmenting active ingredients
FEATURES
High concentration depigmenting actives, effective on all brown spots stages, non-comedogenic, fragrance-free, acts on three factors of dark spots formation, light texture, suitable for all skin types including pregnant women, clinically proven results
BEST FOR
all skin types
CHECKS
No comedogenic ingredients, no fragrance
Who Is It For?
Adults All Genders Suitable For Pregnant Or Breastfeeding WomenWhat Does It Help With?
Brown Spots Pigmentation Uneven Skin ToneBudget
Premium ($76-$150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Ducray Says
Product Description:
Melascreen Anti-spot concentrate is the 1st dermatological solution specially developed to effectively depigment all types of brown spots thanks to a very high concentration of depigmenting dermatological active ingredients (15%). They act directly at 3 different levels on the 3 factors responsible for their formation. Contains Glycolic acid and azelaic acid that are perfectly adapted to offer selective depigmentation even on the most difficult to correct brown spots, this anti-spot concentrate preserves the skin's natural pigmentation. Features include: The 1st Global Dermatological Care Product with very high concentration of depigmenting active ingredients (15%). Visible results in 2 weeks. Effectively depigments all brown spots at every stage of their formation. Non-comedogenic and fragrance free formulation developed to minimise allergic risks. Acts directly at 3 different levels on the 3 factors responsible for dark spots formation. Hesperidine Methylchalcone reduces the size of superficial blood vessels, Azelaic Acid regulates the overproduction of melanin at the source through selective action, Glycolic Acid promotes the elimination of dead surface cells to reduce the intensity of brown spots. It has a light texture, a non-greasy and non-sticky finish with good tolerance suitable for all skin types. Suitable for pregnant or breastfeeding women. Results: 98% reduction in brown spots size and intensity, 96% reduces the appearance of existing brown spots, 94% uniformity and evenness of skin tone (Clinical study on 47 women for 2 months, results after 1 month).
About the Brand:
Ingredients Overview
Ingredients List
Water-(Aqua),Azelaic-Acid,Caprylic/Capric-Triglyceride,Squalane,Propanediol,Glycerin,Glycolic-Acid
Key Ingredients
Azelaic Acid,Hesperidin Methylchalcone,Glycolic Acid
Ingredients Details
Glycerin
Common Name(s): Glycerol,glycerine,1,2,3-propanetriol
CAS Number: 56-81-5
DESCRIPTION
What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.
Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.
How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.
Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners
TECHNICAL DETAILS
Primary Category: Humectant
Secondary Functions: Skin barrier support,emollient,solvent
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ30% (typical: 3โ10%)
SOURCING & ETHICS
Vegan Status: Yes โ plant-derived (coconut, soy, palm) or synthetic
Halal Status: Yes โ when plant-derived or synthetic; verify source with supplier
Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; non-irritating at all standard concentrations
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).
Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas
Avoid Combining With: No known incompatibilities at standard concentrations
SCIENTIFIC NOTE
Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder
Primary Sources: 2026-03-12
Propanediol
Common Name(s): 1,3-propanediol,zemea,bio-propanediol
CAS Number: 504-63-2
DESCRIPTION
What It Does: Provides humectant and solvent functionality from sustainable corn-based fermentation.
Why It's Used: Bio-based propylene glycol alternative from renewable corn โ propanediol provides equivalent functionality to propylene glycol with sustainable renewable feedstock and superior skin feel.
How It Works: Two oh groups provide humectant water binding. excellent solvent for fragrances, actives, and preservatives. mild antimicrobial from diol structure for preservative system boosting. renew corn fermentation origin (dupont zemea process). better skin feel than propylene glycol โ less sticky.
Typically Found In: Virtually all cosmetic categories as pg alternative
TECHNICAL DETAILS
Primary Category: Functional ingredient โ humectant
Secondary Functions: Tewl reduction,skin plumping
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ20%
SOURCING & ETHICS
Vegan Status: Yes โ from corn sugar fermentation
Halal Status: Yes
Source Notes: Synthetic or naturally derived. excellent aqueous solubility.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; suitable for all skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Propanediol's dupont tate & lyle bio products 'zemea' process ferments corn sugar to 1,3-propanediol using engineered e. coli โ one of the first commercially viable bio-fermentation routes to a cosmetic diol previously made only from petroleum. the renewable route produces chemically identical 1,3-propanediol while reducing carbon footprint by approximately 40% vs petrochemical synthesis.
Last Verified: Cosing database,dupont tate & lyle zemea technical data,cir safety assessment
Primary Sources: 2026-03-12
Squalane
Common Name(s): Perhydrosqualene,2,6,10,15,19,23-hexamethyltetracosane
CAS Number: 0111-01-03
DESCRIPTION
What It Does: Provides endogenous-skin-identical emolliency with exceptional stability and skin compatibility.
Why It's Used: The most skin-compatible emollient โ chemically identical to human sebum squalene component with outstanding tolerability across all skin types.
How It Works: Fully saturated hydrocarbon with zero oxidation sites provides exceptional stability unlike squalene's 6 double bonds. integrates into stratum corneum lipid bilayers with near-perfect biocompatibility. provides antioxidant protection to formulation via radical quenching.
Typically Found In: Facial oils,serums,non-comedogenic moisturizers,luxury body care
TECHNICAL DETAILS
Primary Category: Functional ingredient โ emollient
Secondary Functions: Maximum biocompatibility,antioxidant stabilizer,non-comedogenic
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1%โ100%
SOURCING & ETHICS
Vegan Status: Conditional โ plant-derived (sugarcane, olive) preferred; shark liver-derived being phased out
Halal Status: Yes โ plant-derived
Source Notes: Sustainable plant-derived squalane from sugarcane fermentation (amyris) or olive oil fractionation is preferred over shark liver-derived. chemically identical regardless of source.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Squalene constitutes approximately 12-15% of human sebum โ the highest proportion of any skin lipid. topical squalane (stable, hydrogenated form) replenishes this abundant endogenous skin lipid. the complete absence of oxidizable double bonds (unlike squalene's 6 double bonds) eliminates the pro-oxidant concerns of natural squalene oxidation.
Last Verified: Cosing database,huang et al. squalane review,cir safety assessment
Primary Sources: 2026-03-12