Dot & Key Barrier Repair Moisture Stick On-The-Go Spf 50

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class — physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

1-2-hexanediol has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,1-2-hexanediol technical literature

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides antioxidant protection, anti-inflammatory activity, and skin conditioning from polyphenols, terpenoids, and phytochemicals.

Why It's Used: Multi-functional phytochemical profiles support concurrent skin care claims with authentic botanical heritage.

How It Works: Polyphenols scavenge ros, inhibit nf-kb/cox pathways, and condition skin through phytochemical interactions.

Typically Found In: Botanical skin care

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Conditional

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Plant secondary metabolites evolved for uv photoprotection and pathogen defence — mechanisms directly translatable to cosmetic antioxidant and anti-inflammatory activity in human skin.

Last Verified: Cosing database,ceresin botanical review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides essential barrier sterol function as one of three critical stratum corneum lipid components.

Why It's Used: Essential component of complete barrier repair formulations – the stratum corneum barrier requires ceramides:cholesterol:fatty acids in approximately 1:1:1 molar ratio for complete barrier restoration.

How It Works: Integrates between ceramide headgroups in lamellar body structures, providing fluidity and flexibility to the otherwise rigid ceramide-dominated lipid matrix. controls lamellar body phase behavior for functional barrier.

Typically Found In: Barrier repair moisturizers,eczema treatments,dry skin formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – barrier sterol

Secondary Functions: Lamellar body structure,barrier sterol

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–1%

SOURCING & ETHICS

Vegan Status: Conditional – animal-derived (lanolin) or plant-derived phytosterol analogs; verify

Halal Status: Conditional – verify source

Source Notes: Traditionally from lanolin (wool grease). plant-derived cholesterol alternatives include phytosterols, though these show slightly different barrier integration. verify for vegan/halal.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Endogenous molecule; excellent tolerability.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. natural skin component. ewg score: 1.

Works Well With: Other ceramides,cholesterol,free fatty acids,hyaluronic acid,niacinamide

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Elias demonstrated that barrier repair requires all three lipid classes (ceramides, cholesterol, fatty acids) in approximately equimolar ratios. formulations providing only ceramides without cholesterol and fatty acids show significantly inferior barrier restoration vs complete triple-lipid combinations.

Last Verified: Cosing database,elias et al. barrier lipid ratio study,loden barrier repair review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides a dry, weightless application vehicle that evaporates cleanly leaving actives and non-volatile silicones deposited on skin — eliminating the residual heaviness of conventional liquid carrier solvents.

Why It's Used: Cyclosiloxanes are the unique volatile silicone solvents that dissolve non-volatile silicones (dimethicone, cyclomethicone), organic uv filters, and lipophilic actives, providing the sensory-superior dry-touch application experience in premium formulations.

How It Works: Cyclosiloxane vapour pressure (d5 cyclopentasiloxane ~0.3 mmhg at 25°c) provides clean evaporation at body temperature. the cyclic ring structure provides lower boiling point than equivalent linear dimethicone, enabling faster evaporation while the ring conformation maintains the silicone's low surface energy for smooth application.

Typically Found In: Primers,antiperspirants,sunscreens

TECHNICAL DETAILS

Primary Category: Functional ingredient – emollient

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–50%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Cyclopentasiloxane (d5) and cyclohexasiloxane (d6) are under eu regulatory review for potential environmental persistence (pbt assessment) — formulators should monitor eu regulation 2018/35 implementation for restrictions in wash-off products.

Last Verified: Cosing database,eu cyclosiloxane regulatory review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides uvb-uva-ii uv protection and essential avobenzone photostabilisation.

Why It's Used: The essential combination partner — octocrylene's dual uv filter + avobenzone photostabilisation function makes it virtually irreplaceable for durable broad-spectrum chemical sunscreens requiring uva-i coverage.

How It Works: Cyanocinnamate chromophore absorbs uvb-uva-ii (λmax 303nm). triplet energy transfer from excited avobenzone to octocrylene photostabilises avobenzone (>90% efficiency at 3:1 avobenzone:octocrylene ratio). hydrophobic character enhances water resistance.

Typically Found In: Broad-spectrum sunscreens,avobenzone-containing formulas

TECHNICAL DETAILS

Primary Category: Active ingredient – uv filter and photostabiliser

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Up to 10% (eu), 10% (us fda)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu max 10%. fda: 10%. ewg score: 3. recent benzophenone impurity concerns from aged product hydrolysis under study.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Octocrylene's triplet energy transfer photostabilisation of avobenzone operates via a dexter electron exchange mechanism: excited-state avobenzone (triplet) transfers excitation energy to octocrylene via orbital overlap, allowing avobenzone to return to its ground state uv-absorbing form without photodegradation. this energy transfer is only efficient at close molecular proximity — requiring intimate mixing of the two compounds in the formulation oil phase.

Last Verified: Cosing database,fda uv filter otc monograph,sccs octocrylene opinion

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.

Why It's Used: The benchmark cosmetic preservative – eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.

How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.

Typically Found In: All cosmetic formulations as primary preservative

TECHNICAL DETAILS

Primary Category: Functional ingredient – broad-spectrum preservative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–1% (eu max 1%)

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at ≤1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations – a consumer perception issue rather than a scientific safety concern.

Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment

Primary Sources: 2026-03-12