
Highlights
WHAT IS IT?
Face serum with multiple benefits, ingredient count not specified
FEATURES
Treats acne and acne marks, reduces blemishes and dark spots, controls excess oil, unclogs pores and balances pore size, brightens skin tone, boosts hydration levels, strengthens skin barrier, minimizes fine lines and wrinkles
BEST FOR
combination
CHECKS
No information available about preservatives, fragrances, silicones, parabens, sulfates, or PEGs; no confirmed allergen or ingredient absence explicitly stated
Who Is It For?
No Explicit Age Range Or Gender SpecifiedWhat Does It Help With?
Acne Acne Marks Blemishes Dark Spots Excess Oil Control Pore Size Balancing Skin Brightening Hydration Boosting Skin Barrier Strengthening Fine Line And Wrinkle ReductionBudget
Affordable (under $30)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Dermease Says
Product Description:
Dermease 10 Niacinamide Face Serum is a potent formulation that addresses multiple skincare concerns. It effectively treats acne and acne marks, reduces blemishes and dark spots, and controls excess oil production. By unclogging pores and balancing pore size, it promotes smoother skin texture. This serum also brightens skin tone, boosts hydration levels, and strengthens the skin barrier, resulting in a more resilient complexion. Additionally, it minimizes the appearance of fine lines and wrinkles, leaving skin visibly smoother and more youthful.
About the Brand:
Ingredients Overview
Ingredients List
Key Ingredients
Niacinamide,Aloe Vera Extract
Ingredients Details
Niacinamide
Common Name(s): Vitamin b3,nicotinamide,pyridine-3-carboxamide
CAS Number: 98-92-0
DESCRIPTION
What It Does: Niacinamide strengthens the skin barrier, reduces visible pore size, regulates sebum production, fades dark spots, and improves skin texture and tone.
Why It's Used: It is used because it addresses multiple skin concerns at once without irritation, making it suitable for all skin types. it is stable in formulations and pairs well with most other actives.
How It Works: Niacinamide inhibits the transfer of melanosomes (pigment packets) to skin cells, reducing hyperpigmentation. it also stimulates ceramide synthesis to strengthen the skin barrier and reduces inflammation by modulating cytokine activity.
Typically Found In: Serums,moisturizers,toners,cleansers,eye creams,sunscreens,primers
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin
Secondary Functions: Barrier repair,brightening,anti-inflammatory
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 2%โ10% (typical: 5%; higher concentrations may cause flushing in some individuals)
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes โ synthetic origin
Source Notes: Commercially produced via synthesis from nicotinic acid or 3-cyanopyridine. no animal-derived sources used in cosmetic-grade niacinamide.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; concentrations above 10% may cause temporary flushing in sensitive individuals
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: At concentrations >10%, some users experience niacin flush (transient redness/tingling). generally very well-tolerated.
Safe for Sensitive Skin: Yes โ one of the best-tolerated actives for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Extensively studied and considered very safe. ewg hazard score: 1. no significant systemic toxicity concerns at topical concentrations.
Works Well With: Retinol,peptides,ahas/bhas,hyaluronic acid,ceramides,zinc,vitamin c,spf
Avoid Combining With: High concentrations of vitamin c (ascorbic acid) may theoretically convert to niacin โ use at different times if using pure l-ascorbic acid above 15%
SCIENTIFIC NOTE
Niacinamide is a precursor to nad+ and nadp+, coenzymes vital to cellular energy metabolism. its benefits for dna repair and mitochondrial function make it a key ingredient in anti-aging strategies.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,pubmed clinical studies
Primary Sources: 2026-03-12