DERMAFIQUE Perfect pH Facial Cleanser

DESCRIPTION

What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.

Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.

How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix — enzymes, receptors, structural proteins, or signaling molecules — triggering beneficial biological responses.

Typically Found In: Serums,treatments,moisturizers,specialty products

TECHNICAL DETAILS

Primary Category: Specialty actives

Secondary Functions: Skin-conditioning,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Specialty active ingredient; check individual sourcing for vegan status.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides

Avoid Combining With: Incompatible with oxidizing agents; check ph stability

SCIENTIFIC NOTE

Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-γ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides floral-balsamic scent with uv-absorbing fixative properties.

Why It's Used: Natural jasmine-associated fragrance ester with mild uv protection contribution for fragranced sun-exposed products.

How It Works: Salicylate ester absorbs uv-b mildly. provides fixative function by slowing evaporation of lighter fragrance top notes. naturally in jasmine absolute (1-3%). good skin absorption.

Typically Found In: Floral fragrances,sun-exposed products

TECHNICAL DETAILS

Primary Category: Fragrance component – floral fixative

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.001%–1%

SOURCING & ETHICS

Vegan Status: Yes – from jasmine absolute, or synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Eu cosmetics regulation: declared fragrance allergen. ifra guidelines apply.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Benzyl salicylate's salicylate moiety provides uv absorption in the uvb range (absorbs at 295-315nm) despite not being a registered uv filter. its occurrence in jasmine absolute means natural jasmine-fragranced products inherently contain a mild uv absorber – an incidental benefit of the natural fragrance chemistry that wasn't intentionally designed as photoprotection.

Last Verified: Cosing database,ifra standards

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides colour in cosmetic formulations within the permitted application areas and concentrations specified by fda 21 cfr 73/74 and eu cosmetics regulation annex iv.

Why It's Used: Regulatory compliance requires verifying both the permitted use category (fd&c, d&c, ext. d&c) and the specific application area approval for each colorant in each target market.

How It Works: Colour arises from selective wavelength absorption by the chromophore structure — electronic transitions (d-orbital for transition metal pigments; π→π* for organic chromophores) absorb specific visible wavelengths providing the perceived complementary colour.

Typically Found In: Colour cosmetics

TECHNICAL DETAILS

Primary Category: Active ingredient – mineral / metal active

Secondary Functions: Antimicrobial,sebum regulation,antioxidant enzyme cofactor

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Per product type — check fda/eu permitted list

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Conditional

Source Notes: Mineral/inorganic compound. cosmetic or pharmaceutical grade.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating at recommended concentrations.

Safe for Sensitive Skin: Yes at recommended concentrations

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile at cosmetic concentrations. ewg score: 1–2.

Works Well With: Niacinamide,salicylic acid,other actives

Avoid Combining With: No significant incompatibilities at standard concentrations

SCIENTIFIC NOTE

All cosmetic colorants in the us require fda batch certification confirming identity and purity per lot — uncertified batches cannot legally appear in finished us cosmetics. eu annex iv lists permitted colorants with specific maximum concentrations and use restrictions by product category.

Last Verified: Fda 21 cfr 73/74,eu cosmetics regulation annex iv,colorant regulatory review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Boosts foam, enhances mildness, and conditions skin and hair when combined with primary surfactants.

Why It's Used: The standard foam booster and mildness enhancer in virtually all shampoos, body washes, and facial cleansers – provides synergistic mildness improvement with anionic surfactants.

How It Works: Amphoteric (zwitterionic) character provides positive charge interaction with hair keratin for antistatic conditioning. reduces irritation of co-formulated anionic surfactants via ionic complex formation. foam stabilization via bilayer reinforcement in foam lamellae.

Typically Found In: Shampoos,body washes,facial cleansers,baby products

TECHNICAL DETAILS

Primary Category: Functional ingredient – amphoteric surfactant

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 2%–15%

SOURCING & ETHICS

Vegan Status: Yes – from coconut fatty acids and dimethylaminopropylamine

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Capb's mildness-enhancing synergy with sls has a molecular mechanism: capb's positive imidazoline head group forms an ion pair complex with sls's anionic sulfate group, reducing sls's free monomer concentration (the irritation-causing species) without significantly reducing micelle-forming capacity (the cleansing species).

Last Verified: Cosing database,ananthapadmanabhan surfactant review,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides gentle non-ionic cleansing from natural glucose-derived surfactant chemistry.

Why It's Used: Leading natural-origin surfactant for green/natural formulations requiring gentle, non-ionic cleansing with excellent biodegradability credentials.

How It Works: Non-ionic surfactant with glucoside headgroup and decyl (c10) chain provides mild cleansing via micelle formation. non-ionic character provides lower irritation potential than anionic surfactants. fully biodegradable and from renewable sources.

Typically Found In: Natural cleansers,baby products,green beauty formulas,scalp cleansers

TECHNICAL DETAILS

Primary Category: Functional ingredient – alkyl glucoside surfactant

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 2%–20%

SOURCING & ETHICS

Vegan Status: Yes – from glucose (plant) and fatty alcohols

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Alkyl glucosides' (apgs) non-ionic character means they have no electrical charge that could interact with skin surface proteins and phospholipids – a key reason for their exceptional mildness. ionic surfactants (sulfates, carboxylates) bind to positively charged protein lysine/arginine residues causing denaturation; apgs have no such binding affinity.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Dissolves and fixes fragrance components in cosmetic formulations, acts as an alcohol denaturant, and provides film plasticisation in nail products.

Why It's Used: Dep is the only phthalate still permitted in cosmetics — formulators must distinguish dep (permitted) from dbp, dehp, and dinp (restricted/prohibited in eu and california) to maintain compliance.

How It Works: The short ethyl chain of dep provides moderate lipophilicity (logp 1.4) for fragrance solubilisation without the endocrine disruption concerns of longer-chain phthalates (dbp logp 4.5; dehp logp 7.3). the ester oxygen provides h-bonding for fragrance component interaction.

Typically Found In: Fragrance products,nail products

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 5%–15%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Eu cosmetics regulation does not restrict dep; however sccs has reviewed phthalates collectively. formulators should monitor evolving regulatory position — california's proposition 65 lists some phthalates and consumer-facing 'phthalate-free' positioning is increasingly common regardless of dep's current permitted status.

Last Verified: Cosing database,sccs phthalate review,dep fragrance solvent

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides broad-spectrum preservation against bacteria and fungi through controlled formaldehyde release, maintaining product safety throughout shelf life at eu-permitted concentrations.

Why It's Used: Formaldehyde-releasing preservatives provide reliable broad-spectrum preservation but face increasing consumer and regulatory scrutiny — eu requires label declaration, and many brands adopt 'formaldehyde-free' positioning due to sensitisation concerns.

How It Works: Hydrolysis in aqueous formulation releases formaldehyde (hcho) at controlled rates depending on ph and temperature. free formaldehyde cross-links bacterial proteins and nucleic acids through schiff base formation with amine groups, providing bactericidal activity. sensitisation risk from free formaldehyde's reactivity with skin proteins forming haptens.

Typically Found In: All aqueous formulations

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Check eu annex v limits

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Eu regulation 1223/2009 requires 'contains formaldehyde' label declaration when free formaldehyde >0.05% in the finished product. many formulators are transitioning away from formaldehyde-releasing preservatives to avoid this label requirement regardless of safety profile.

Last Verified: Cosing database,eu annex v formaldehyde-releasing preservative declaration

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides the complete fragrance profile contributing to product sensory experience and consumer appeal.

Why It's Used: Fragrance is a major consumer purchase driver — up to 70% of consumers make purchasing decisions partially based on product scent.

How It Works: Fragrance blends interact with olfactory receptors providing the sensory profile — complex mixtures activate multiple receptor types for rich, multidimensional scent experiences.

Typically Found In: All fragrance products

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Standard use levels

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ifra guidelines set usage limits for fragrance ingredients based on skin sensitisation and phototoxicity assessment for each application category.

Last Verified: Eu regulation 1223/2009 annex iii,ifra standards,fragrance allergen declaration requirements

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–30% (typical: 3–10%)

SOURCING & ETHICS

Vegan Status: Yes – plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes – when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12