DERMA E
DERMA E Scalp Relief Conditioner
Derma E's Scalp Relief Conditioner contains a doctor-developed, clinically-tested formula that works in four ways to gently cleanse, deflake, soothe and nourish the scalp and hair.
Sulfate-free
Paraben-free
Color-safe
Silicone-free
Natural
Dryness
Optimized for Your Environment & Lifestyle
Nykaa
In stock
Recommended
DERMA E Scalp Relief Conditioner
DERMA E
derma-e-scalp-relief-conditioner
Conditioner
10365020373285
Morning or Evening?
How often will you use this product?
Notes
Secure payment protection
Your Biodata Compatibility Analysis
Based on your 6 hair health indices and environmental factors
Poor Match
Significant incompatibilities
Growth Cycle Health Index
Hair Match
Hair Health Index Alignment
Optimal for OSI, SSI, DI, HSI
Ingredient Efficacy
Matching Ingredient Score
Environment Compatibility
Current UV, Air Quality & Humidity
Why This Works for Your Specific Profile
Damage Index:
Damaged hair structure cannot withstand product intensity causing increased breakage and further compromise
Water Quality:
Fine hair becomes weighed down and greasy from heavy formulation
Hair:
Porous structure over-absorbs product leading to buildup, stiffness, or excessive dryness
Active Lifestyle:
High activity and frequent washing rapidly strip product benefits requiring excessive reapplication
Your Hair Profile Integration
Your Hair Archetype
Density Level
Washing Frequency
Shedding Level
Oil Level
Your Hair Health Indices
Oil Secretion (OSI)
Very low oil production
Scalp Sensitivity (SSI)
Very low sensitivity
Growth Rate (CMR)
Poor metabolism rate
Damage Index (DI)
Minimal damage
Hair Strength (HSI)
Very weak strength
Softness Index (SI)
Significant improvement needed
Water & Environmental Integration
Water:
Expected Results & Timeline
Key Highlights
What is it?
Conditioner with multiple ingredients
Who Is It For
All ages and genders
Budget
$13.00 - $26.00
Timeline
Works best after 7 days of use
Why Youโll Love It
What Does It Help With?
Dryness, Scalp Issues
Best for
Scalp Issues
Features
Gently detangles, de-flakes, soothes and nourishes the scalp and hair; Safe for color-treated hair; Recyclable & wind energy certified; Formulated without GMOs, gluten, or soy
Checks
Vegan, Cruelty Free, Sustainable Packaging
Ingredients Overview
Ingredients List
purified-water, cetyl-alcohol-plant-derived, glycerin-vegetable-derived, behentrimonium-chloride, coco-caprylate-coconut-derived, salix-alba-white-willow-bark-extract, diheptyl-succinate, capryloyl-glycerin-sebacic-acid-copolymer, epilobium-angustifolium-canadian-willowherb-extract, organic-chamomilla-recutita-matricaria-flower-extract, menthol, salicylic-acid, arctium-lappa-burdock-root-extract, zanthoxylum-zanthoxyloides-fagara-bark-extract, arctostaphylos-uva-ursi-bearberry-leaf-extract, melia-azadirachta-neem-leaf-extract, coptis-chinensis-chinese-goldthread-root-extract, panthenol-provitamin-b5, prunus-amygdalus-dulcis-sweet-almond-oil, melaleuca-alternifolia-tea-tree-leaf-oil, organic-argania-spinsosa-argan-kernel-oil, organic-aloe-barbadensis-aloe-vera-gel-extract, retinyl-palmitate-vitamin-a, tocopheryl-acetate-vitamin-e, phenoxyethanol, ethylhexylglycerin
Key Ingredients
therapeutic-herbal-blend-neem-burdock-and-bearberry, tea-tree-and-menthol, salicylic-acid, white-willow-bark-extract, aloe-vera-extract, vitamins-a-and-e, provitamin-b5-panthenol
Ingredients Details
Ethylhexylglycerin
Common Name(s): Octylglycerin,2-ethylhexyl glycerol ether,sensiva sc 10
CAS Number: 70445-33-9
DESCRIPTION
What It Does: Provides antimicrobial skin conditioning with deodorant activity and preservation system enhancement.
Why It's Used: Multifunctional clean beauty preservation active โ ethylhexylglycerin provides antimicrobial, deodorant, and skin conditioning in a single ingredient accepted in most natural cosmetic certification schemes.
How It Works: Glycerol ether provides antimicrobial via bacterial membrane phospholipid disruption. deodorant activity via reduction of underarm lipase enzyme activity (similar mechanism to triethyl citrate). skin conditioning from glycerol humectant component. synergistic with phenoxyethanol and diols.
Typically Found In: Natural preservation systems,deodorants,skin conditioning products
TECHNICAL DETAILS
Primary Category: Functional ingredient โ antimicrobial glycerol ether
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ2.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Ethylhexylglycerin's deodorant mechanism is pharmacologically identical to triethyl citrate: both inhibit skin surface microbial lipase enzymes that convert odourless triglycerides to odorous free fatty acids. the glycerol ether structure of ethylhexylglycerin, combined with the 2-ethylhexyl chain, provides lipase inhibition similar to ester-based lipase inhibitors from a different chemical class.
Last Verified: Cosing database,schรผlke sensiva sc 10 technical data,cir safety assessment
Primary Sources: 2026-03-12
Menthol
Common Name(s): L-menthol,peppermint camphor,(-)-menthol
CAS Number: 89-78-1
DESCRIPTION
What It Does: Activates trpm8 cold thermoreceptors for intense cooling sensation and analgesic activity.
Why It's Used: The most potent cosmetic cooling agent โ direct trpm8 agonist providing cooling sensation without actual temperature reduction for refreshing and analgesic formulations.
How It Works: Potent trpm8 (menthol receptor/cold thermosensor) agonist โ activation at room temperature mimics cold sensation without actual cooling. anti-pruritic via trpm8 activation competing with itch c-fiber signaling. antimicrobial via membrane disruption.
Typically Found In: Cooling products,scalp treatments,oral care,pain relief,foot care,after-sun
TECHNICAL DETAILS
Primary Category: Active ingredient โ cooling sensory terpenoid
Secondary Functions: Redness reduction,anti-inflammatory,calming
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ from mentha piperita or synthetic
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 2/5 โ low to moderate; potential sensitizer
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.
Safe for Sensitive Skin: Avoid near eyes. use with caution at concentrations above 1% for sensitive skin.
SAFETY & COMPATIBILITY
Safety Profile: Eu max 4.5% (leave-on); regulations vary by application site. avoid on infants' face.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Menthol's exceptional cooling potency stems from its ec50 for trpm8 activation of approximately 10ฮผm (vs camphor's ec50 of ~5mm โ 500ร lower potency). this 500ร potency advantage explains why even tiny concentrations of menthol provide intense cooling, while much higher concentrations of camphor are required for equivalent sensation.
Last Verified: Cosing database,mckemy et al. menthol trpm8 discovery,cir safety assessment
Primary Sources: 2026-03-12
Phenoxyethanol
Common Name(s): 2-phenoxyethanol,rose ether,ethylene glycol monophenyl ether
CAS Number: 122-99-6
DESCRIPTION
What It Does: Prevents microbial contamination and spoilage in cosmetic formulations.
Why It's Used: The benchmark cosmetic preservative โ eu-permitted up to 1%, effective against virtually all cosmetically relevant microorganisms, and excellent tolerability.
How It Works: Phenol ring provides broad antimicrobial activity via disruption of bacterial and fungal cell membranes and inhibition of enzymatic activity. effective against gram-positive and gram-negative bacteria, yeasts (candida), and molds (aspergillus). activity ph range: 3-9.
Typically Found In: All cosmetic formulations as primary preservative
TECHNICAL DETAILS
Primary Category: Functional ingredient โ broad-spectrum preservative
Secondary Functions: Skin conditioning
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ1% (eu max 1%)
SOURCING & ETHICS
Vegan Status: Yes โ synthetic
Halal Status: Yes
Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Well-tolerated by most skin types.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Eu cosmetics regulation max 1%. sccs assessed as safe at โค1%. avoid use around eyes in baby products per some country regulations. ewg score: 4.
Works Well With: Standard skincare actives
Avoid Combining With: No known significant incompatibilities
SCIENTIFIC NOTE
Phenoxyethanol's widespread adoption as the primary cosmetic preservative followed the phaseout of parabens from many formulations in the 2000s-2010s. despite having a comparable or better safety profile to parabens, it is often cited in 'free-from' formulations โ a consumer perception issue rather than a scientific safety concern.
Last Verified: Cosing database,sccs opinion on phenoxyethanol,cir safety assessment
Primary Sources: 2026-03-12
Personalized Usage Instructions
How to Use
Step 1
Apply to freshly shampooed hair and scalp
Step 2
Allow product to penetrate for 2-3 minutes
Step 3
Rinse, towel dry, then style as usual
Medical Chemicals
Protein/Moisture
- Moisture
pH Level
- Acidic
Porosity Taget
- Normal Porosity
Customized for Your Profile
Scalp Condtions
Anti-Dandruff, Sensitive Scalp, pH Balanced, Dry Scalp
Climate Suitability
Humid, Dry, Hard Water, Soft Water, Winter, Summer
Clinical Claims
Doctor-developed, clinically-tested formula
Frequency
Apply to freshly shampooed hair and scalp. Allow product to penetrate for 2-3 minutes. Rinse, towel dry, then style as usual.
Product Information
Vegan
Cruelty Free
Sustainable Packaging