Citra Uv Body Lotion Supple & Bright Sakura 210Ml

DESCRIPTION

What It Does: Inhibits neuromuscular acetylcholine release for reduced facial muscle contraction and expression line formation.

Why It's Used: Enhanced argireline analog with improved stability for formulations requiring optimized neuro-inhibiting anti-wrinkle performance.

How It Works: Competes with snap-25 protein for binding to the snare complex, reducing vesicular acetylcholine release at neuromuscular junctions. reduced acetylcholine binding decreases muscle contraction amplitude, reducing expression line depth with repeated use.

Typically Found In: Anti-wrinkle creams,expression line treatments,forehead/eye area products

TECHNICAL DETAILS

Primary Category: Active ingredient – neurotransmitter-inhibiting peptide

Secondary Functions: Enhanced snare inhibition,improved stability

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 3–1000 ppm

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetically produced. encapsulation may improve delivery to neuromuscular junction.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Exceptional safety profile. ewg score: 1.

Works Well With: Hyaluronic acid,ceramides,retinol,moisturizers

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Hexapeptide-8 differs from argireline (hexapeptide-3) in its c-terminal modification that increases resistance to enzymatic degradation by skin proteases. this improved stability extends the bioavailability of the active peptide at the neuromuscular junction, potentially improving clinical anti-wrinkle efficacy vs the original argireline.

Last Verified: Cosing database,lipotec argireline plus data

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Delivers targeted skin-conditioning or bioactive benefits through a specific mechanism of action suited to the formulation's intended purpose.

Why It's Used: Specialty actives address specific skin concerns through targeted molecular mechanisms, providing efficacy beyond what base formulation ingredients alone can achieve.

How It Works: The bioactive compound interacts with specific molecular targets in skin cells or the extracellular matrix — enzymes, receptors, structural proteins, or signaling molecules — triggering beneficial biological responses.

Typically Found In: Serums,treatments,moisturizers,specialty products

TECHNICAL DETAILS

Primary Category: Specialty actives

Secondary Functions: Skin-conditioning,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01–5%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Specialty active ingredient; check individual sourcing for vegan status.

SKIN COMPATIBILITY

Irritancy Rating: 1

Comedogenicity Rating: 0

Sensitivity Concerns: Low sensitization potential at recommended use concentrations.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Well-characterized cosmetic ingredient with established safety profile. generally non-irritating at typical use concentrations. suitable for leave-on and rinse-off cosmetics.

Works Well With: Niacinamide,hyaluronic acid,vitamin c,peptides

Avoid Combining With: Incompatible with oxidizing agents; check ph stability

SCIENTIFIC NOTE

Specialty actives typically work through enzyme inhibition (e.g., tyrosinase inhibition for brightening, mmp inhibition for anti-aging), receptor activation (e.g., retinoid receptors, ppar-γ for barrier genes), or transcription factor modulation (e.g., nrf2 for antioxidant gene upregulation). structure-activity relationships determine potency and selectivity.

Last Verified: Cosing eu database; pcpc cosmetic ingredient safety reviews; ingredient-specific safety and efficacy literature

Primary Sources: 2025-01-15

DESCRIPTION

What It Does: Provides humectant hydration and active ingredient solubilization with excellent skin feel.

Why It's Used: Preferred glycol humectant in premium and k-beauty formulations for superior skin feel vs propylene glycol with equivalent functionality.

How It Works: Two hydroxyl groups at 1,3-positions provide water binding and solvent activity. better tolerated than propylene glycol with minimal sensitization risk. 4-carbon backbone provides slightly greater hydrophobic character enabling dissolution of less polar actives vs pg.

Typically Found In: Toners,essences,serums,k-beauty formulas

TECHNICAL DETAILS

Primary Category: Functional ingredient – glycol humectant

Secondary Functions: Tewl reduction,skin plumping

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–10%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Synthetic or naturally derived. excellent aqueous solubility.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; suitable for all skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,emollients,occlusives,glycerin,hyaluronic acid

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

K-beauty's preference for butylene glycol over propylene glycol is driven by two factors: bg's superior skin feel (less tacky than pg's higher viscosity) and its lower sensitization potential (1,3-bg has better spatial distribution of hydroxyl groups that reduces protein interaction vs pg's 1,2-position oh groups).

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides transparent gel textures and thickening at very low concentrations via ph-responsive swelling.

Why It's Used: The most widely used gel thickener – provides crystal-clear, stable gels at concentrations as low as 0.1-0.5% with ph-controlled viscosity.

How It Works: Highly crosslinked polyacrylic acid remains tightly coiled at acidic ph. neutralization with naoh or triethanolamine ionizes carboxylic groups causing electrostatic repulsion that unfolds and swells the polymer coils, dramatically increasing viscosity. concentration-dependent thickening.

Typically Found In: Gels,serums,emulsions,sunscreens

TECHNICAL DETAILS

Primary Category: Functional ingredient – polyacrylic acid thickener

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–2%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Carbomer's ph-responsive swelling mechanism provides an elegant formulation control tool: a neutralized gel can be liquefied by ph reduction (adding acid) and re-thickened by reneutralization. this reversible rheology control allows two-phase products that mix on application without the need for mechanical emulsification.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides c16 fatty alcohol emolliency and thickening for well-textured cosmetic emulsions.

Why It's Used: Lighter-textured fatty alcohol alternative to stearyl alcohol for creams and conditioners requiring less heavy emolliency.

How It Works: C16 chain length provides slightly lower melting point (49°c) than stearyl (60°c) giving softer, lighter emulsion texture. forms lamellar networks for thickening and stability. direct skin and hair conditioning via fatty alcohol film.

Typically Found In: Creams,hair conditioners,lotions

TECHNICAL DETAILS

Primary Category: Functional ingredient – fatty alcohol

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%–15%

SOURCING & ETHICS

Vegan Status: Yes – from vegetable or coconut/palm fatty acids

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Cetyl alcohol's c16 chain length is at the approximate thermal transition point for fatty alcohol lamellar crystallization at skin temperature (33°c). this transition (from ordered crystalline to disordered liquid phase near skin temperature) provides the characteristic 'melts on application' sensory profile that makes cetyl alcohol-containing products feel cooling and light on initial application.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides emollient conditioning from sc-compatible fatty acid triglycerides supporting barrier lipid supplementation and ceramide precursor delivery.

Why It's Used: Curcuma aromatica root oil is selected for the distinctive triglyceride fatty acid profile of curcuma aromatica — the specific oleic, linoleic, and saturated fatty acid ratio determines the spreading speed, occlusion level, and sc barrier integration properties unique to this botanical oil.

How It Works: Fatty acid triglycerides integrate into sc: oleic provides fluid emolliency; linoleic serves as ceramide precursor; alpha-linolenic provides anti-inflammatory competition.

Typically Found In: Skin care,barrier repair

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%–30%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Conditional

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Verify efa composition and oxidative stability for the target application.

Last Verified: Cosing database,curcuma aromatica root oil botanical oil review

Primary Sources: 2026-03-22

DESCRIPTION

What It Does: Provides silicone-characteristic silky feel and skin protection with adjustable viscosity.

Why It's Used: The benchmark cosmetic silicone – sets the gold standard for silky application feel, spreadability, and skin protection in virtually all skin care categories.

How It Works: Polydimethylsiloxane chain flexibility provides extremely low surface tension and high spreadability. inert si-o backbone provides chemical stability and excellent skin tolerance. occlusive film formation reduces tewl. higher viscosity grades provide more intense conditioning.

Typically Found In: Moisturizers,foundations,primers,sunscreens – nearly universal

TECHNICAL DETAILS

Primary Category: Functional ingredient – polydimethylsiloxane

Secondary Functions: Barrier sealing,softening

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–30%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Plant-derived, synthetic or animal-derived. verify source.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 1/5 – low; formulation-dependent

Sensitivity Concerns: Non-irritating.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Humectants,ceramides,actives as carrier

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Dimethicone's exceptional silky feel arises from its very low intermolecular attractive forces (weak van der waals forces due to non-polar methyl groups) that allow silicone chains to slide freely over skin. the coefficient of kinetic friction for pdms against skin (~0.04) is among the lowest of any cosmetic material – explaining why even small amounts transform product feel.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides metal ion chelation to prevent product degradation and boost preservative and antioxidant efficacy.

Why It's Used: The most essential stability ingredient in cosmetics — disodium edta's metal chelation prevents rancidity, discoloration, and preservative failure caused by trace metal contamination in virtually all aqueous cosmetic formulations.

How It Works: Ethylenediaminetetraacetic acid provides six potential coordination sites for metal ions (aminodiacetate groups). chelates ca²⁺, mg²⁺ (stability), fe³⁺ (fenton radical prevention), cu²⁺ (oxidase inhibition). disrupts gram-negative bacterial outer membrane by chelating membrane calcium, enhancing preservative penetration.

Typically Found In: Virtually all aqueous cosmetics — creams, lotions, shampoos, toners

TECHNICAL DETAILS

Primary Category: Functional ingredient – chelating agent

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.005%–0.1%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Disodium edta's preservative potentiation against gram-negative bacteria is mechanistically elegant: gram-negative outer membranes contain lipopolysaccharide stabilised by calcium and magnesium bridges. edta chelates these metal ions, destabilising the lps layer and creating pores that allow hydrophobic preservatives (phenoxyethanol, parabens) to penetrate — converting gram-negative-resistant preservatives into broad-spectrum ones.

Last Verified: Cosing database,cir safety assessment

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Absorbs uv radiation at specific wavelengths (uva 320–400 nm, uvb 290–320 nm) and dissipates photon energy as heat rather than skin-damaging photochemical reactions.

Why It's Used: Organic uv filters are chosen for their high molar extinction coefficient, specific spectral coverage, and formulation compatibility — individual filters are combined to provide broad-spectrum coverage across uva+uvb.

How It Works: Uv photon absorption by the aromatic chromophore π-system excites the molecule from s₀ ground state to s₁ excited state. rapid internal conversion or photoisomerisation dissipates energy as vibrational heat before it can initiate skin photodamage.

Typically Found In: Sunscreens,photoprotective products

TECHNICAL DETAILS

Primary Category: Active ingredient – cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: Check local sunscreen regulations

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Organic uv filters require photostabilisation (by avobenzone-octocrylene pairing, or triazine stabilisers) as some absorbers degrade on uv exposure — formulator must verify photostability of the chosen filter combination.

Last Verified: Cosing database,ethylhexyl methoxycinnamate organic uv filter review

Primary Sources: 2026-03-12

DESCRIPTION

What It Does: Provides antimicrobial skin conditioning with deodorant activity and preservation system enhancement.

Why It's Used: Multifunctional clean beauty preservation active — ethylhexylglycerin provides antimicrobial, deodorant, and skin conditioning in a single ingredient accepted in most natural cosmetic certification schemes.

How It Works: Glycerol ether provides antimicrobial via bacterial membrane phospholipid disruption. deodorant activity via reduction of underarm lipase enzyme activity (similar mechanism to triethyl citrate). skin conditioning from glycerol humectant component. synergistic with phenoxyethanol and diols.

Typically Found In: Natural preservation systems,deodorants,skin conditioning products

TECHNICAL DETAILS

Primary Category: Functional ingredient – antimicrobial glycerol ether

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%–0.5%

SOURCING & ETHICS

Vegan Status: Yes – synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1–2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethylhexylglycerin's deodorant mechanism is pharmacologically identical to triethyl citrate: both inhibit skin surface microbial lipase enzymes that convert odourless triglycerides to odorous free fatty acids. the glycerol ether structure of ethylhexylglycerin, combined with the 2-ethylhexyl chain, provides lipase inhibition similar to ester-based lipase inhibitors from a different chemical class.

Last Verified: Cosing database,schülke sensiva sc 10 technical data,cir safety assessment

Primary Sources: 2026-03-12