Bio-essence
Bio-essence Bio-Age Luxe Smart Precision Ampoule
Bio-essence Bio-Age Luxe Smart Precision Ampoule
Bio-essence
bio-essence-bio-age-luxe-smart-precision-ampoule
Serum
10084811768101
Morning or Evening?
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Highlights
WHAT IS IT?
Serum with 8 active ingredients
FEATURES
Firms skin, provides intense moisture, reduces lines and wrinkles, helps with pigmentation and wrinkles, gentle and fragrance-free
BEST FOR
sensitive
CHECKS
Strong allergen-free, Fragrance-free
Who Is It For?
What Does It Help With?
Firming Skin Moisture Reducing Lines Wrinkles Pigmentation Dark Spots Skin Texture And FirmnessBudget
Premium ($76-$150)How To Use
Which routine should it be used in?
Instructions:
Key Information
What Bio-essence Says
Product Description:
Explore the entire range of Serums & Essence available on Nykaa. Shop more Bio-essence products here. You can browse through the complete world of Bio-essence Serums & Essence.
About the Brand:
Ingredients Overview
Ingredients List
Retinoid-A,Vitamin-E,Sodium-Hyaluronate,Vitamin-C,Euglena-Gracilis-extract,Sodium-Lactate,Allantoin,Niacinamide
Key Ingredients
Retinoid-A, Vitamin E, Sodium Hyaluronate, Vitamin C, Euglena Gracilis extract, Sodium Lactate, Allantoin, Niacinamide
Ingredients Details
Allantoin
Common Name(s): 5-ureidohydantoin,glyoxyldiureide,aluminum dihydroxy allantoinate
CAS Number: 97-59-6
DESCRIPTION
What It Does: Soothes irritation, accelerates wound healing, promotes skin cell renewal, and provides mild keratolytic exfoliation.
Why It's Used: Gold standard multi-function soothing active โ one of the most widely used cosmetic ingredients across all product types for its exceptional tolerability and clinically proven multi-action skin conditioning.
How It Works: Promotes keratinocyte proliferation and fibroblast migration for wound healing. mild keratolytic activity by disrupting corneocyte binding. anti-irritant via direct protein binding and anti-inflammatory cytokine reduction. humectant activity via hydroxyl groups.
Typically Found In: Post-procedure products,sensitive skin formulas,wound care,anti-acne treatments,baby products
TECHNICAL DETAILS
Primary Category: Active ingredient โ soothing / anti-inflammatory
Secondary Functions: Wound healing,keratolytic,anti-irritant
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ2%
SOURCING & ETHICS
Vegan Status: Yes โ synthetic or comfrey-derived
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Exceptionally well-tolerated; suitable for all skin types including baby and compromised skin.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Allantoin's keratinocyte proliferation stimulation occurs via receptor-mediated signaling (possibly machr activation) rather than non-specific irritation-driven proliferation, making it a true wound-healing stimulant rather than a pro-inflammatory proliferative signal.
Last Verified: Cosing database,cir safety assessment,araรบjo et al. allantoin review
Primary Sources: 2026-03-12
Niacinamide
Common Name(s): Vitamin b3,nicotinamide,pyridine-3-carboxamide
CAS Number: 98-92-0
DESCRIPTION
What It Does: Niacinamide strengthens the skin barrier, reduces visible pore size, regulates sebum production, fades dark spots, and improves skin texture and tone.
Why It's Used: It is used because it addresses multiple skin concerns at once without irritation, making it suitable for all skin types. it is stable in formulations and pairs well with most other actives.
How It Works: Niacinamide inhibits the transfer of melanosomes (pigment packets) to skin cells, reducing hyperpigmentation. it also stimulates ceramide synthesis to strengthen the skin barrier and reduces inflammation by modulating cytokine activity.
Typically Found In: Serums,moisturizers,toners,cleansers,eye creams,sunscreens,primers
TECHNICAL DETAILS
Primary Category: Active ingredient โ vitamin
Secondary Functions: Barrier repair,brightening,anti-inflammatory
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 2%โ10% (typical: 5%; higher concentrations may cause flushing in some individuals)
SOURCING & ETHICS
Vegan Status: Yes โ synthetically produced
Halal Status: Yes โ synthetic origin
Source Notes: Commercially produced via synthesis from nicotinic acid or 3-cyanopyridine. no animal-derived sources used in cosmetic-grade niacinamide.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low; concentrations above 10% may cause temporary flushing in sensitive individuals
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: At concentrations >10%, some users experience niacin flush (transient redness/tingling). generally very well-tolerated.
Safe for Sensitive Skin: Yes โ one of the best-tolerated actives for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Extensively studied and considered very safe. ewg hazard score: 1. no significant systemic toxicity concerns at topical concentrations.
Works Well With: Retinol,peptides,ahas/bhas,hyaluronic acid,ceramides,zinc,vitamin c,spf
Avoid Combining With: High concentrations of vitamin c (ascorbic acid) may theoretically convert to niacin โ use at different times if using pure l-ascorbic acid above 15%
SCIENTIFIC NOTE
Niacinamide is a precursor to nad+ and nadp+, coenzymes vital to cellular energy metabolism. its benefits for dna repair and mitochondrial function make it a key ingredient in anti-aging strategies.
Last Verified: Cosing database,cir safety assessment,ewg skin deep,pubmed clinical studies
Primary Sources: 2026-03-12