Acne Relief Gentle & Soothing Cleanser

Perricone MD

Acne Relief Gentle & Soothing Cleanser

Acne Relief Gentle & Soothing Cleanser

Perricone MD

acne-relief-gentle-soothing-cleanser

Cleanse

9643628069157

Morning or Evening?

Morning
Evening
Both

How often will you use this product?

Everyday
Every other day
Every 3 days
Every 4 days
Every 5 days
Every 6 days
Once a week
Twice a week
On specific days
As needed
On rotation

Notes

Add to Routine
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Compatibility Score

0%

Microbiome
Ingredients
Biological
Environment
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How It Fits Into Your Skincare Routine

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Highlights

WHAT IS IT?

Gentle cleanser with 12 ingredients

FEATURES

Non-foaming formula, unclogs pores, removes acne-causing debris without over-drying

BEST FOR

Sensitive, acne-prone skin

CHECKS

Does not contain fragrance

Who Is It For?

Above 18 Both Women And Men

What Does It Help With?

Acne Excess Oil Clogged Pores

Budget

Mid-range

How To Use

Which routine should it be used in?

Morning
Evening
 
Cleanse
Tone
Eyecare
Serum
Moisturize
Suncare
 

Instructions:

Lather a quarter-sized amount in hands and gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning and ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

Key Information

Vegan
Cruelty-free
Sensitive-safe
Non-comedogenic
Hypoallergenic
Microbiome-safe
Preservative-free
Eco-friendly
Pregnancy-safe
Oil-free

What Perricone MD Says

Product Description:

The Gentle & Soothing Cleanser is Step 1 in your regimen, to be used both day and night for fighting acne-causing bacteria. The non-foaming formula thoroughly cleanses, reduces excess oil, unclogs pores, removes dead skin cells and eliminates debris without irritating sensitive, acne-prone skin. Ultra-fine sucrose supports a healthy surface skin microbiome, yet rinses off quickly and easily, while squalane hydrates without making skin look or feel greasy.

About the Brand:

Founded by Dr. Nicholas Perricone, Perricone MD is a pioneer in the science of aging. This brand takes a holistic approach to skincare, combining cutting-edge ingredients with a focus on nutrition and lifestyle. Experience transformative results with products that address not just the signs of aging, but its underlying causes.

Ingredients Overview

Ingredients List

Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Silylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Key Ingredients

Sucrose, Squalane

Ingredients Details

C13-14 Isoparaffin

Common Name(s): C13-14 isoparaffin,c13-14 isoparaffin,cosmetic functional ingredient,established active

CAS Number: N/a

DESCRIPTION

What It Does: Provides lightweight non-polar emolliency from the hydrocarbon chain.

Why It's Used: C13-14 isoparaffin is selected for hydrocarbon emolliency โ€” the non-polar alkane or alkene chain provides clean-rinse lightweight conditioning with no ester or silicone residue for formulators seeking a minimal-footprint emollient.

How It Works: Hydrocarbon chain: non-polar โ†’ low surface energy โ†’ fast-spreading emolliency; no ester or silicone chemistry โ†’ clean formulation profile.

Typically Found In: Cosmetic formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Safety documented in cosing at standard formulation concentrations.

Last Verified: Cosing database,c13-14 isoparaffin technical review

Primary Sources: 2026-03-22

Caprylyl Glycol

Common Name(s): 1,2-octanediol,octanediol,sensiva sc 50

CAS Number: 1117-86-8

DESCRIPTION

What It Does: Provides the most potent antimicrobial diol activity alongside skin feel enhancement.

Why It's Used: Premium antimicrobial diol โ€” caprylyl glycol's c8 chain provides the strongest membrane-disrupting antimicrobial activity of common diol preservative boosters with unique skin-feel enhancement.

How It Works: C8 1,2-diol: c8 chain length provides strongest bacterial and fungal membrane disruption of common diols. emollient skin feel improvement from c8 chain length interaction with skin surface. active at lower concentrations than shorter-chain diols. synergistic with ethylhexylglycerin.

Typically Found In: Natural preservation systems,skin feel enhancement

TECHNICAL DETAILS

Primary Category: Functional ingredient โ€“ antimicrobial humectant

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“1%

SOURCING & ETHICS

Vegan Status: Yes โ€“ synthetic

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Caprylyl glycol's antimicrobial potency follows the chain-length dependent membrane activity of fatty acids: c8 is the optimal chain length for membrane disruption (same as caprylic acid's antimicrobial optimum), providing maximum membrane integration without the skin sensitisation associated with longer chain lengths. this chain-length pharmacophore relationship is why c8 > c6 > c5 in diol antimicrobial potency despite identical head group chemistry.

Last Verified: Cosing database,schรผlke sensiva sc 50 technical data,cir safety assessment

Primary Sources: 2026-03-12

Ethylhexyl Palmitate

Common Name(s): Ethylhexyl palmitate,cosmetic active,functional ingredient

CAS Number: N/a

DESCRIPTION

What It Does: Delivers characteristic cosmetic function at recommended use concentration.

Why It's Used: Selected for functional contribution and formulation compatibility supported by cosmetic science and regulatory safety data.

How It Works: Works through the mechanism of its molecular class โ€” physicochemical or biological interaction with skin proteins, lipids, or receptors as documented in peer-reviewed cosmetic literature.

Typically Found In: Skin care formulations

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ cosmetic active

Secondary Functions: Skin conditioning

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“10%

SOURCING & ETHICS

Vegan Status: Conditional

Halal Status: Yes

Source Notes: Commercially produced for cosmetic use. verify vegan/halal status with supplier.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Well-tolerated by most skin types.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Good safety profile at recommended concentrations. ewg score: 1โ€“2.

Works Well With: Standard skincare actives

Avoid Combining With: No known significant incompatibilities

SCIENTIFIC NOTE

Ethylhexyl palmitate has an established safety and efficacy profile within the cosmetic regulatory framework at standard use concentrations.

Last Verified: Cosing database,ethylhexyl palmitate technical literature

Primary Sources: 2026-03-12

Glycerin

Common Name(s): Glycerol,glycerine,1,2,3-propanetriol

CAS Number: 56-81-5

DESCRIPTION

What It Does: Glycerin pulls water from the environment and deeper skin layers into the outer skin layer (epidermis), boosting moisture levels and keeping skin soft, smooth, and plump.

Why It's Used: It is used in virtually every moisturizer, serum, and cleanser because it is highly effective at hydrating skin, is well-tolerated by all skin types, and enhances the texture and spreadability of formulations.

How It Works: As a humectant, glycerin forms hydrogen bonds with water molecules, trapping them in the skin. it also reinforces the skin barrier by integrating into lipid structures between skin cells.

Typically Found In: Moisturizers,serums,cleansers,toners,sheet masks,sunscreens,body lotions,shampoos,conditioners

TECHNICAL DETAILS

Primary Category: Humectant

Secondary Functions: Skin barrier support,emollient,solvent

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 1%โ€“30% (typical: 3โ€“10%)

SOURCING & ETHICS

Vegan Status: Yes โ€“ plant-derived (coconut, soy, palm) or synthetic

Halal Status: Yes โ€“ when plant-derived or synthetic; verify source with supplier

Source Notes: Derived from plant oils via hydrolysis or saponification; synthetic versions also available. palm-derived glycerin carries sustainability concerns.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low; non-irritating at all standard concentrations

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Extremely rare allergic reactions; generally safe for all skin types including sensitive and baby skin

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Widely recognized as safe. ewg hazard score: 1. no significant concerns for irritation, sensitization, or toxicity at typical concentrations (up to 50%).

Works Well With: Hyaluronic acid,ceramides,niacinamide,panthenol,urea,peptides,retinol,ahas/bhas

Avoid Combining With: No known incompatibilities at standard concentrations

SCIENTIFIC NOTE

Glycerin is an endogenous skin component found naturally in the stratum corneum. aquaporin-3 channels in keratinocytes facilitate glycerin transport, making it integral to natural skin hydration pathways.

Last Verified: Cosing database,cir safety assessment,ewg skin deep,inci decoder

Primary Sources: 2026-03-12