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TRIMETHYLAMINE OXIDE

Description

Trimethylamine oxide (TMAO) is an organic compound gaining attention in skincare for its potential protective and hydrating properties. This small, water-soluble molecule is naturally found in marine organisms, where it helps maintain cellular function under high-pressure environments. In skincare applications, TMAO acts as an osmolyte, regulating cellular water balance and protecting against osmotic stress.

TMAO's ability to stabilize proteins and maintain cell volume makes it a promising ingredient for addressing skin hydration and barrier function. It may help improve skin's resilience to environmental stressors and dehydration. Research suggests TMAO can enhance the skin's natural moisturizing factor (NMF), potentially leading to improved skin hydration and elasticity.

In formulations, TMAO is typically used at concentrations between 0.5% to 2%. It is compatible with a wide range of skincare ingredients and can be incorporated into various product types, including serums, moisturizers, and masks. While more clinical studies are needed to fully elucidate its benefits in topical applications, preliminary data indicate TMAO could be a valuable addition to hydrating and protective skincare formulations, particularly for dry or stressed skin.