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TEUPOLIOSIDE

Description

Teupolioside is a novel phenylethanoid glycoside isolated from the aerial parts of Ajuga tenorei, a plant species native to southern Italy. This compound has garnered attention in dermatological research due to its potential therapeutic properties. Structurally, teupolioside consists of a caffeic acid moiety linked to a ��-glucopyranose unit through an ester bond.

Studies have shown that teupolioside exhibits significant anti-inflammatory and antioxidant activities, making it a promising ingredient for skincare formulations targeting inflammatory skin conditions and oxidative stress-induced damage. Its anti-inflammatory effects are partly attributed to its ability to inhibit pro-inflammatory cytokine production and modulate NF-��B signaling pathways.

In vitro experiments have demonstrated teupolioside's capacity to protect skin cells against UV-induced damage, suggesting its potential use in photoprotective formulations. Additionally, preliminary research indicates that teupolioside may possess mild antimicrobial properties, which could be beneficial in managing acne-prone skin.

The compound's water solubility and stability in aqueous solutions make it suitable for incorporation into various skincare product formats. However, further clinical studies are necessary to fully elucidate teupolioside's efficacy, optimal concentration, and long-term safety profile in topical applications.