
TETRAMETHYLBUTYL DIHYDROXYBENZAMIDE
Description
Tetramethylbutyl dihydroxybenzamide, also known as Thiamidol, is a novel skin-lightening agent that has gained attention in the dermatological field for its efficacy and safety profile. This synthetic compound works by inhibiting tyrosinase, the key enzyme responsible for melanin production in the skin. Unlike hydroquinone, which has been associated with safety concerns, tetramethylbutyl dihydroxybenzamide offers a gentler approach to addressing hyperpigmentation and uneven skin tone.
Clinical studies have demonstrated that tetramethylbutyl dihydroxybenzamide can effectively reduce the appearance of dark spots and melasma within 4-8 weeks of regular use. Its mechanism of action involves selectively targeting melanocytes without causing cellular toxicity, making it suitable for long-term use. The ingredient has shown good stability in various formulations and is typically used at concentrations between 0.2% to 2%.
Tetramethylbutyl dihydroxybenzamide is compatible with other skincare actives, including antioxidants and moisturizing agents, allowing for versatile product formulations. It has a low irritation potential, making it appropriate for sensitive skin types. As with all skin-lightening agents, sunscreen use is essential when incorporating this ingredient into a skincare regimen to prevent UV-induced repigmentation.