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Stearyl Glycyrrhetinate

Description

Stearyl Glycyrrhetinate is a potent anti-inflammatory compound derived from licorice root extract. This ingredient is a synthetic ester of glycyrrhetinic acid, the active component responsible for licorice's soothing properties. It exhibits remarkable skin-calming effects, making it valuable in treating various dermatological conditions and in cosmetic formulations.

The compound works by inhibiting key enzymes involved in the inflammatory process, particularly 11β-hydroxysteroid dehydrogenase. This action helps reduce redness, itching, and irritation associated with sensitive or inflamed skin. Stearyl Glycyrrhetinate also demonstrates mild antimicrobial properties, potentially aiding in managing acne-prone skin.

In skincare products, it is often used at concentrations between 0.1% and 1%. Its lipophilic nature allows for improved skin penetration and prolonged effectiveness compared to water-soluble alternatives. Stearyl Glycyrrhetinate is compatible with a wide range of cosmetic ingredients and remains stable in most formulations.

Clinical studies have shown its efficacy in alleviating symptoms of atopic dermatitis, eczema, and psoriasis. Additionally, it may help in reducing post-inflammatory hyperpigmentation and supporting the skin's natural barrier function. These properties make Stearyl Glycyrrhetinate a versatile ingredient in both therapeutic and cosmetic skincare applications.