Back to Ingredient Dictionary

Sh-Polypeptide-121

Description

Sh-Polypeptide-121 is an innovative synthetic peptide designed to target multiple aspects of skin aging and regeneration. This biomimetic compound is engineered to closely resemble naturally occurring growth factors in human skin, particularly those involved in cellular communication and repair processes.

The peptide's structure allows it to penetrate the skin's outer layers effectively, where it can interact with cellular receptors. Upon binding, Sh-Polypeptide-121 initiates a cascade of signaling events that stimulate collagen and elastin production, enhance cellular turnover, and promote the synthesis of extracellular matrix components.

Clinical studies have demonstrated Sh-Polypeptide-121's ability to improve skin firmness, elasticity, and overall texture. It has shown particular efficacy in reducing the appearance of fine lines and wrinkles, as well as enhancing skin hydration and barrier function.

The ingredient is typically used in low concentrations (0.001% to 0.01%) due to its potency. It is compatible with a wide range of cosmetic formulations, including serums, creams, and lotions. Sh-Polypeptide-121 is generally well-tolerated, making it suitable for various skin types, including sensitive skin. However, as with any active ingredient, patch testing is recommended before full application.