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AMINOGUANIDINE BICARBONATE

Description

Aminoguanidine bicarbonate is a versatile compound gaining attention in skincare formulations for its potential anti-aging and protective properties. This ingredient, also known as pimagedine, is a nucleophilic hydrazine derivative that primarily functions as an advanced glycation end-product (AGE) inhibitor.

In skincare, aminoguanidine bicarbonate works by interfering with the glycation process, which is a key factor in skin aging. Glycation occurs when sugar molecules bind to proteins like collagen and elastin, leading to the formation of AGEs. These AGEs contribute to skin stiffness, loss of elasticity, and the appearance of wrinkles.

The compound's ability to inhibit AGE formation may help preserve skin structure and maintain a more youthful appearance. Additionally, aminoguanidine bicarbonate has shown potential as an antioxidant, offering protection against free radical damage. Its mild alkaline nature can also assist in maintaining optimal skin pH.

Formulators typically incorporate aminoguanidine bicarbonate at concentrations ranging from 0.1% to 1% in anti-aging serums, creams, and other topical products. While promising, further research is needed to fully elucidate its long-term efficacy and safety profile in various skincare applications.