Back to Ingredient Dictionary

ACYL COENZYME A DESATURASE

Description

ACYL COENZYME A DESATURASE is a critical enzyme involved in fatty acid metabolism, playing a pivotal role in skin health and barrier function. This enzyme catalyzes the introduction of double bonds into saturated fatty acyl-CoAs, producing monounsaturated fatty acids. In skincare formulations, ingredients that modulate or mimic the activity of Acyl Coenzyme A Desaturase can significantly impact skin lipid composition and function.

The enzyme's activity is particularly important for maintaining skin hydration, elasticity, and protection against environmental stressors. By influencing the ratio of saturated to unsaturated fatty acids in skin cells, it helps optimize membrane fluidity and permeability. This, in turn, supports the skin's barrier function, reducing transepidermal water loss and enhancing resistance to irritants and pathogens.

In cosmetic applications, compounds that interact with or support Acyl Coenzyme A Desaturase activity may be incorporated to improve skin texture, increase moisturization, and enhance overall skin health. These ingredients can be particularly beneficial in formulations targeting dry, sensitive, or aging skin, where maintaining optimal lipid balance is crucial for skin function and appearance.