Common Name(s): Ziyu glycoside iii,ziyu glycoside iii,sanguisorba triterpenoid saponin,wound healing active

CAS Number: N/a

DESCRIPTION

What It Does: Provides sanguisorba triterpenoid saponin haemostatic activity, keratinocyte proliferation stimulation for wound healing, and anti-inflammatory activity from the pomolic acid glycoside scaffold.

Why It's Used: Ziyu glycoside iii is selected for sanguisorba triterpenoid saponin wound healing activity — the ziyu glycoside series provides a graduated pharmacological profile across glycosides i–iii, with combined haemostatic, proliferative, and anti-inflammatory activity for skin repair formulations.

How It Works: Ziyu glycoside iii: triterpenoid sapogenin (pomolic acid) → nf-kb anti-inflammatory; saponin surfactant property → keratinocyte membrane interaction → proliferation stimulation; haemostatic activity via platelet aggregation.

Typically Found In: Wound healing,anti-inflammatory,repair care

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.05%–2%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Ziyu glycosides i–iii differ in the sugar moiety — glycoside i (monodesmoside) vs ii/iii (bidesmosides) providing different bioavailability and skin penetration profiles.

Last Verified: 2026-03-22

Primary Sources: Cosing database,ziyu glycoside iii sanguisorba saponin review