Common Name(s): Uracil,uracil,nucleobase,skin cell dna/rna repair support
CAS Number: N/a
DESCRIPTION
What It Does: Provides uracil nucleobase substrate for skin cell dna repair, rna synthesis, or purine catabolism regulation depending on the specific nucleobase pharmacology.
Why It's Used: Uracil is selected for its nucleobase-mediated cell metabolism support — providing the specific pyrimidine or purine substrate that activates dna repair, rna synthesis, or energy metabolism pathways relevant to anti-aging and cellular maintenance.
How It Works: Uracil: nucleobase salvage pathway → nucleotide synthesis → dna/rna synthesis; cell cycle support → keratinocyte turnover normalisation; purine/pyrimidine substrate delivery.
Typically Found In: Anti-aging,cell repair
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.05%–3%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Uracil is absorbed via nucleobase transporters in keratinocytes — the salvage pathway provides an energy-efficient route to nucleotide synthesis bypassing de novo biosynthesis.
Last Verified: 2026-03-22
Primary Sources: Cosing database,uracil nucleobase cell metabolism review