Back to Ingredient Dictionary

TETRAPEPTIDE-46

Description

Tetrapeptide-46 is a synthetic peptide composed of four amino acids, specifically designed to target skin inflammation and improve barrier function. This innovative ingredient has gained attention in the skincare industry for its potential to address multiple concerns associated with sensitive and compromised skin.

The primary mechanism of action for Tetrapeptide-46 involves modulating the skin's inflammatory response by inhibiting the release of pro-inflammatory cytokines. This action helps to reduce redness, irritation, and discomfort commonly experienced in reactive skin conditions. Additionally, the peptide has been shown to enhance the production of key proteins essential for maintaining a healthy skin barrier, including filaggrin and involucrin.

Research indicates that Tetrapeptide-46 may be particularly beneficial for individuals with atopic dermatitis, rosacea, or generally sensitive skin. Its ability to strengthen the skin barrier can lead to improved hydration retention and reduced susceptibility to external irritants. In formulations, Tetrapeptide-46 is typically used at low concentrations, ranging from 0.002% to 0.005%, making it a potent yet gentle option for addressing skin sensitivity and inflammation.