Common Name(s): Sh-pentapeptide-5,sh-pentapeptide-5,synthetic biology peptide,engineered signal peptide
CAS Number: N/a
DESCRIPTION
What It Does: Provides receptor-specific signal peptide activity through the bio-identical sequence enabling precise gene-level collagen synthesis, mmp inhibition, or barrier repair.
Why It's Used: Sh-pentapeptide-5 delivers precision receptor pharmacology — the sh/sr designation confirming synthetic or recombinant manufacture for maximum purity and batch reproducibility.
How It Works: Synthetic peptide: spps or recombinant expression → sequence-specific receptor binding → intracellular signalling → target gene expression modulation.
Typically Found In: Anti-aging,precision skin care
TECHNICAL DETAILS
Primary Category: Active ingredient – peptide
Secondary Functions: Collagen synthesis,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.0005%–2%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetically produced via solid-phase peptide synthesis (spps).
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating at recommended concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Retinoids,niacinamide,vitamin c,hyaluronic acid
Avoid Combining With: Strong acids below ph 3.5; oxidising agents
SCIENTIFIC NOTE
Synthetic biology peptides provide the ultimate batch-to-batch reproducibility versus plant-extracted peptide fractions.
Last Verified: 2026-03-22
Primary Sources: Cosing database,sh-pentapeptide-5 synthetic peptide review