
SH-DS PHOSPHOROTHIOATE RNA-2 CHOLESTEROL
Description
SH-DS Phosphorothioate RNA-2 Cholesterol is an advanced bioactive ingredient that combines RNA technology with cholesterol for enhanced skin penetration and cellular uptake. This novel compound consists of a short hairpin RNA (shRNA) sequence modified with phosphorothioate bonds and conjugated to cholesterol.
The phosphorothioate modification increases the stability of the RNA molecule, protecting it from degradation by nucleases present in the skin. This allows for prolonged activity and improved efficacy. The cholesterol conjugation facilitates passage through cell membranes, enabling better intracellular delivery of the RNA.
Once inside skin cells, SH-DS Phosphorothioate RNA-2 Cholesterol can potentially modulate gene expression related to various skin functions, including collagen production, melanin synthesis, and inflammatory responses. This targeted approach may lead to improvements in skin texture, tone, and overall appearance.
The ingredient shows promise in addressing multiple skin concerns, such as aging, hyperpigmentation, and inflammation. However, as with all RNA-based therapies, careful consideration must be given to potential off-target effects and long-term safety. Further clinical studies are needed to fully elucidate its efficacy and optimal use in skincare formulations.