Common Name(s): Rna,rna,nucleic acid,cell communication molecule
CAS Number: N/a
DESCRIPTION
What It Does: Provides nucleoside and nucleobase delivery for adenosine receptor stimulation, nad+ precursor contribution, and cell energy metabolism support.
Why It's Used: Rna is selected for nucleic acid-mediated cell communication — rna and dna fragments activate toll-like receptor signalling for skin immunity modulation and provide purine/pyrimidine bases as nad+ and energy cofactor precursors.
How It Works: Nucleic acid fragment → tlr3 activation (dsrna) or tlr9 activation (cpg dna) → interferon signalling or a2a adenosine receptor binding → collagen fibroblast stimulation.
Typically Found In: Anti-aging,cell communication
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Rna/dna cosmetic ingredients are hydrolysed to nucleosides/bases in formulation — the biologically active species are the purine/pyrimidine mononucleotides released by hydrolysis.
Last Verified: 2026-03-22
Primary Sources: Cosing database,rna nucleic acid skin active review