Common Name(s): Vitamin a linoleate,retinol linoleate

CAS Number: 74685-29-3

DESCRIPTION

What It Does: Delivers combined vitamin a cell-renewal and linoleic acid barrier-repair benefits.

Why It's Used: Dual-action retinoid for acne-prone skin: vitamin a cell renewal plus linoleic acid for sebum normalization.

How It Works: Hydrolyzed to retinol (cell turnover) and linoleic acid (barrier ceramide synthesis and anti-comedogenic sebum normalization).

Typically Found In: Anti-aging serums,acne-prone formulations,barrier repair

TECHNICAL DETAILS

Primary Category: Active ingredient – vitamin a derivative

Secondary Functions: Barrier repair,sebum regulation

Application Areas:

Typical Concentration Range: 0.01%–0.5%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Synthetic or from plant-based linoleic acid esterified with retinol. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic; linoleic acid is anti-comedogenic

Sensitivity Concerns: Introduce slowly; retinization expected at higher potencies.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Safe at cosmetic concentrations. use spf. avoid during pregnancy. ewg score: 2.

Works Well With: Niacinamide,ceramides,hyaluronic acid,spf,tocopherol

Avoid Combining With: Pregnancy; extended uv without spf; benzoyl peroxide

SCIENTIFIC NOTE

Linoleic acid deficiency in sebum is causally associated with comedone formation. retinyl linoleate delivers the retinoid and essential fatty acid simultaneously.

Last Verified: 2026-03-12

Primary Sources: Cosing database,cir safety assessment