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Common Name(s): Recoflavone,recoflavone,genistein dimer,anti-aging isoflavone

CAS Number: N/a

DESCRIPTION

What It Does: Provides er-beta selective phytoestrogenic activation for collagen synthesis, hyaluronic acid upregulation, and antioxidant gene expression with enhanced formulation stability.

Why It's Used: Recoflavone is selected for improved genistein pharmacology — the structural modification over free genistein provides superior oxidative stability in aqueous formulas and enhanced skin penetration while retaining the er-beta agonism that drives collagen synthesis.

How It Works: Isoflavone chromone → er-beta selective binding → collagen i/iii + ha synthase gene activation; antioxidant: flavonoid catechol radical scavenging.

Typically Found In: Anti-aging,menopausal skin

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.05%–2%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Recoflavone's modified structure addresses the rapid oxidative instability of free genistein in aqueous formulations — the structural modification providing a shelf-stable phytoestrogenic active.

Last Verified: 2026-03-22

Primary Sources: Cosing database,recoflavone genistein analog anti-aging isoflavone review