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Polyaminopropyl Biguanide

Description

Polyaminopropyl Biguanide (PHMB) is a synthetic antimicrobial agent widely used in skincare and cosmetic products. This water-soluble compound is known for its broad-spectrum effectiveness against bacteria, fungi, and certain viruses. PHMB functions by disrupting microbial cell membranes, leading to cell death and preventing the growth of harmful microorganisms on the skin.

In skincare formulations, PHMB typically serves as a preservative, helping to extend product shelf life and maintain product integrity. Its efficacy at low concentrations (usually 0.1% to 0.3%) makes it an attractive option for formulators. PHMB is particularly valued for its ability to remain stable across a wide pH range and its compatibility with various cosmetic ingredients.

Studies have shown PHMB to be well-tolerated by most skin types, with a low risk of irritation or sensitization. Its non-volatile nature contributes to its long-lasting antimicrobial effects on the skin's surface. Additionally, PHMB has been found to have wound-healing properties, making it beneficial in products designed for compromised skin barriers.

While generally considered safe for use in leave-on and rinse-off products, regulatory bodies like the European Commission have established maximum concentration limits to ensure consumer safety.