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Pentapeptide-18

Description

Pentapeptide-18, also known as Leuphasyl, is a synthetic peptide composed of five amino acids that has gained significant attention in the skincare industry for its potential anti-aging properties. This small molecule is designed to mimic the effects of natural enkephalins, which are involved in neurotransmission and pain modulation.

In skincare formulations, Pentapeptide-18 functions as a neuromodulator, targeting muscle contractions that contribute to the formation of expression lines and wrinkles. It works by inhibiting the release of acetylcholine, a neurotransmitter responsible for muscle contractions, thereby reducing the appearance of fine lines and wrinkles, particularly around the eyes and forehead.

Studies have shown that Pentapeptide-18 can effectively decrease wrinkle depth and improve skin smoothness when used in concentrations of 0.005% to 0.01%. It is often combined with other peptides or active ingredients to enhance its efficacy. This ingredient is generally well-tolerated and suitable for various skin types.

Pentapeptide-18 is typically incorporated into serums, creams, and eye products aimed at addressing signs of aging. Its ability to work synergistically with other anti-aging compounds makes it a valuable addition to advanced skincare formulations.