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OXODEOXY GUANOSINE

Description

Oxodeoxyguanosine, also known as 8-oxo-dG or 8-hydroxy-2'-deoxyguanosine, is a biomarker of oxidative stress and DNA damage in the skin. This molecule is formed when reactive oxygen species (ROS) attack the DNA base guanine, resulting in a modified nucleoside. Its presence in skin cells indicates the level of oxidative damage occurring within the tissue.

In skincare formulations, oxodeoxyguanosine is utilized for its potential to protect against and repair UV-induced DNA damage. It functions as an antioxidant, helping to neutralize free radicals and reduce oxidative stress in skin cells. This ingredient may contribute to improved skin resilience and a reduction in visible signs of aging caused by environmental stressors.

Research suggests that topical application of oxodeoxyguanosine can enhance DNA repair mechanisms in the skin, potentially reducing the risk of mutations that could lead to skin cancer. It may also help in maintaining skin integrity and promoting a more youthful appearance by supporting cellular health.

When incorporated into skincare products, oxodeoxyguanosine is typically used in low concentrations due to its potent effects. It is often combined with other antioxidants and DNA repair enzymes for synergistic benefits in anti-aging and protective formulations.