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Common Name(s): Oligopeptide-88,oligopeptide-88,anti-aging signal oligopeptide,skin conditioning active
CAS Number: N/a
DESCRIPTION
What It Does: Provides receptor-mediated anti-aging activity โ stimulating collagen synthesis, inhibiting mmp degradation, or modulating specific skin receptor pathways at ppm concentrations.
Why It's Used: Oligopeptide sequences provide precise receptor pharmacology from defined molecular structures โ mechanism-based efficacy claims from quantifiable receptor-ligand interactions.
How It Works: Oligopeptide sequence โ receptor active site binding โ intracellular signalling โ col1a1/col3a1 upregulation + mmp inhibition. spps synthesis provides >98% purity for reproducible pharmacological response.
Typically Found In: Anti-aging serums,specialty actives
TECHNICAL DETAILS
Primary Category: Active ingredient โ peptide
Secondary Functions: Collagen synthesis,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 1โ5000 ppm
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Synthetically produced via solid-phase peptide synthesis (spps).
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating at recommended concentrations.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Retinoids,niacinamide,vitamin c,hyaluronic acid
Avoid Combining With: Strong acids below ph 3.5; oxidising agents
SCIENTIFIC NOTE
Oligopeptide inci numbering: each assigned number from the cosing registry designates a unique amino acid sequence โ the numbered series enables targeting of different receptor subtypes across the full oligopeptide catalogue.
Last Verified: 2026-03-22
Primary Sources: Cosing database,oligopeptide-88 anti-aging review