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NORDIHYDROGUAIARETIC ACID

Description

Nordihydroguaiaretic acid (NDGA) is a potent antioxidant compound derived from the creosote bush (Larrea tridentata), a plant native to North American deserts. This polyphenolic lignan has gained attention in the skincare industry for its multifaceted benefits. NDGA exhibits strong free radical scavenging properties, effectively neutralizing reactive oxygen species that contribute to premature skin aging and cellular damage.

In skincare formulations, NDGA demonstrates anti-inflammatory effects, potentially alleviating redness and irritation associated with various skin conditions. Its ability to inhibit lipoxygenase enzymes may contribute to reduced skin inflammation and improved barrier function. NDGA has also shown promise in regulating melanin production, suggesting potential applications in addressing hyperpigmentation and uneven skin tone.

Research indicates that NDGA may possess anti-tumor properties, inhibiting the growth of certain cancer cells, though further studies are needed to fully elucidate its mechanisms in this context. When incorporated into topical products, NDGA's stability and penetration should be carefully considered to maximize its efficacy. As with any potent active ingredient, patch testing is recommended to ensure skin compatibility before widespread use.