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NONAPEPTIDE-37

Description

Nonapeptide-37 is an innovative synthetic peptide designed for advanced haircare formulations. This small protein fragment consists of nine specific amino acids, carefully sequenced to target hair follicle function and promote hair growth. Its primary mechanism of action involves modulating the expression of genes associated with hair cycle regulation and follicular stem cell activity.

In vitro studies have demonstrated that Nonapeptide-37 can stimulate the proliferation of dermal papilla cells, which play a crucial role in hair growth and maintenance. It also appears to upregulate the expression of growth factors such as IGF-1 and KGF, known to support hair follicle health and function.

Clinical trials have shown promising results, with participants experiencing increased hair density and improved hair shaft thickness after regular application of products containing Nonapeptide-37. The peptide is typically incorporated into leave-on treatments such as serums, lotions, or scalp sprays at concentrations ranging from 10 to 100 ppm.

Nonapeptide-37 is generally well-tolerated and can be combined with other hair growth actives like minoxidil or procapil for potentially synergistic effects. Its stability in formulations and ability to penetrate the scalp make it a valuable ingredient in addressing hair thinning and promoting overall hair health.