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Common Name(s): Nitrosomonas eutropha,nitrosomonas eutropha,ammonia-oxidising bacteria,microbiome restoration anti-aging bacteria

CAS Number: N/a

DESCRIPTION

What It Does: Restores the skin's ammonia-oxidising bacteria (aob) microbiome depleted by modern hygiene โ€” producing nitric oxide from sweat ammonia for anti-inflammatory vasodilation, reducing skin surface ph, and re-establishing the pre-modern skin ecology associated with lower inflammatory skin disease prevalence.

Why It's Used: Nitrosomonas represents the 'missing microbiome' of modern skin โ€” the depletion of aob by detergent cleansing removes the primary skin no production pathway. restoration provides the same anti-inflammatory nitric oxide benefits documented in traditional skin microbiome studies.

How It Works: N. eutropha ammonia oxidation: nhโ‚ƒ + oโ‚‚ + nadh โ†’ nhโ‚‚oh (hydroxylamine) โ†’ noโ‚‚โป + no. no โ†’ sgc โ†’ cgmp โ†’ pkg โ†’ vasodilation, anti-inflammatory, antimicrobial. the restored aob microbiome provides continuous no production from sweat/urea substrate, maintaining the skin's endogenous anti-inflammatory signalling.

Typically Found In: Microbiome skin care,anti-inflammatory,natural skin ecology

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ skin microbiome support

Secondary Functions: Microbiome balance,prebiotic effect

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%โ€“1%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Fermentation-derived or plant-extracted.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,niacinamide,soothing actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Nitrosomonas commercial formulations: aobiome developed a topical n. eutropha spray (ao+ spray) โ€” clinical studies showing reduced skin inflammation and improved microbiome diversity in atopic dermatitis and rosacea patients with restored aob colonisation.

Last Verified: 2026-03-22

Primary Sources: Cosing database,nitrosomonas eutropha aob microbiome nitric oxide anti-inflammatory review