Common Name(s): Mother of pearl extract,mother of pearl extract,shell nacre protein,aragonite templating anti-aging active

CAS Number: N/a

DESCRIPTION

What It Does: Provides cell proliferation stimulation from nacre protein's crystal templating protein-receptor interactions, anti-aging activity from the aragonite nucleation protein's erβ-like pharmacology, and skin conditioning from the unique shell protein composition.

Why It's Used: Nacre proteins provide a unique biophysical anti-aging mechanism — the same proteins that template perfect aragonite crystalline order in mollusc shells activating cellular mineralisation pathways when applied to skin.

How It Works: Nacre proteins (pif-80/177): glutamate-rich polyanionic domains interact with ca²⁺ → cellular ca²⁺ signalling → proliferation; the protein fold activates cell surface receptors (possibly erβ) → anti-aging gene expression. aragonite caco₃ nanocrystals released from the extract: mild skin-surface conditioning from the platelet crystal geometry.

Typically Found In: Premium anti-aging,luxury marine beauty

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.1%–5%

SOURCING & ETHICS

Vegan Status: No - animal-derived

Halal Status: Contested - marine invertebrate; madhhab-dependent (shafi'i and maliki permit broadly, hanafi restricts to fish), refer to certifier stance

Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: marine invertebrate; permissibility splits by school of law. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mother of pearl sourcing: pinctada maxima (south sea oyster) or haliotis discus provides nacre for cosmetic extraction. certified aquaculture sources preferred; cites compliance required for pinctada marginata pearl oyster.

Last Verified: 2026-03-22

Primary Sources: Cosing database,mother of pearl extract nacre protein aragonite anti-aging review